700877-55-0
Chemical Structure
Bidenoside C
- CAS No.: 700877-55-0
- Formula:C16H22O6
- Molecular Weight:310.34
InChIKey: QIFYDSMWESCVBZ-JNDSXIQISA-N
SMILES: C/C=C\C#CC#CCCCO[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO
Biological Activity: Bidenoside C is a polyacetylene glycoside found in Coreopsis lanceolata (Asteraceae). Bidenoside C increases AMPK phosphorylation and inhibits adipogenesis and lipid accumulation in preadipocytes. Bidenoside C downregulates the expression of the adipogenic gene SREBP1 and upregulates the expression of the lipolytic gene ATGL. Bidenoside C weakly inhibits LPS (HY-D1056)-induced nitric oxide production in mouse macrophages. Bidenoside C can be used in obesity-related research[1][2][3].
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Bidenoside C | Bidenoside C is a polyacetylene glycoside found in Coreopsis lanceolata (Asteraceae). Bidenoside C increases AMPK phosphorylation and inhibits adipogenesis and lipid accumulation in preadipocytes. Bidenoside C downregulates the expression of the adipogenic gene SREBP1 and upregulates the expression of the lipolytic gene ATGL. Bidenoside C weakly inhibits LPS (HY-D1056)-induced nitric oxide production in mouse macrophages. Bidenoside C can be used in obesity-related research. | |||||||||||||||||||||
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References
- [1]. Baek SC, et al. Anti-Adipogenic Polyacetylene Glycosides from the Florets of Safflower (Carthamus tinctorius). Biomedicines 2021, 9, 91 [Internet]. 2021
- [2]. He J, et al. New polyacetylene glucosides from the florets of Carthamus tinctorius and their weak anti-inflammatory activities. Carbohydrate research. 2011 Sep 27;346(13):1903-8.
- [3]. Kim BR, et al. Constituents of Coreopsis lanceolata Flower and Their Dipeptidyl Peptidase IV Inhibitory Effects. Molecules. 2020 Sep 23;25(19):4370. [Content Brief]
