90 Results for "

prolactin

" in MedChemExpress (MCE) Product Catalog:
Products (90)

90 Results for "prolactin" in MCE Product Catalog:

  • Recombinant Proteins Recommended:
5
5 Cited Publications
Cat. No.: HY-P700261
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PRL; PPRL; prolactin; GHA1; Luteotropic Hormone; Decidual prolactin; prolactin Peptide; Growth Hormone A1; Luteotropin
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3
3 Cited Publications
Cat. No.: HY-P71059
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PRL; PPRL; prolactin; GHA1; Luteotropic Hormone; Decidual prolactin; prolactin Peptide; Growth Hormone A1; Luteotropin
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2
2 Cited Publications
Cat. No.: HY-B1033
CAS No.: 17692-51-2
Metergoline is a serotonin (5-HT) receptor and dopamine receptors antagonist, with pKis of 8.64, 8.75 and 8.75 for 5-HT2A, 5-HT2B and 5-HT2C, respectively. Metergoline is a high-affinity ligand for the h5-HT7 receptor, with a Ki of 16 nM. Metergoline is also a reversible neural Na + channels inhibitor. Metergoline is commonly used for the research of seasonal affective disorder, prolactin hormone regulation .
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1
1 Cited Publications
Cat. No.: HY-P700292
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PRL; PPRL; prolactin; GHA1; Luteotropic Hormone; Decidual prolactin; prolactin Peptide; Growth Hormone A1; Luteotropin
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1
1 Cited Publications
Cat. No.: HY-P71082
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: S100A6; Protein S100-A6; Prev. CACY; S100 Calcium-Binding Protein A6 (Calcyclin); PRA; S100 Calcium-Binding Protein A6; Calcyclin; S100 Calcium-Binding Protein; CABP; Protein S100; 2A9; S10A6; prolactin Receptor-Associated Protein; 5B10; Growth Factor-Ind
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Cat. No.: HY-12713
CAS No.: 18016-80-3
Purity:  99.85%
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

Lisuride is an orally active dopamine D2 receptors agonist. Lisuride, as an ergot derivative, can be used for the research of Parkinson's disease, migraine, and high prolactin levels .
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Cat. No.: HY-W010128
CAS No.: 938-55-6
Synonyms: 6-Dimethylaminopurine; 6-DMAP
6-(Dimethylamino) purine (6-Dimethylaminopurine) is a serine threonine protein kinase inhibitor. 6-(Dimethylamino) purine can inhibit prolactin induced expression of lactoprotein genes in rabbit mammary gland cells. 6-(Dimethylamino) purine can affect the maturation of mammalian oocytes. 6-(Dimethylamino) purine can lead to downregulation of genes related to cell proliferation and cell cycle progression, such as proliferating cell nuclear antigen, insulin-like gene 1, and serine protease inhibitor 2 genes, and induce apoptosis in lymphoma cells (apoptosis) .
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Cat. No.: HY-B1904
CAS No.: 5002-47-1
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

Fluphenazine decanoate is a CNS-penetrant dopamine D2 receptor inhibitor, is a long-acting phenothiazine neuroleptic. Fluphenazine can be used for schizophrenia research .
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Cat. No.: HY-P1530
CAS No.: 235433-36-0
Target:  

Peptides

Research Areas:  

Neurological Disease

Prolactin Releasing Peptide (12-31), human is a fragment of the prolactin releasing peptide (PrRP). Prolactin Releasing Peptide (1-31), human is a high affinity GPR10 ligand that cause the release of the prolactin.
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Cat. No.: HY-U00051
CAS No.: 362-29-8
Propiomazine is an orally active antihistamine agent. Propiomazine is a potent prolactin (PRL) release stimulant, whose effect depends on the antagonism of the dopaminergic system and can inhibit the secretion of luteinizing hormone (LH). Propiomazine is mainly used for anesthesia assistance, mental disorders and anxiety-induced sedation, and can also be used in research related to insomnia .
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Cat. No.: HY-P1174
CAS No.: 100111-07-7
Target:  

GnRH Receptor

Research Areas:  

Endocrinology

GnRH Associated Peptide (GAP) (1-13), human is an amino acid peptide fragment derived from GnRH. GAP can increase the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in rat anterior pituitary cells. GAP also inhibit the secretion of prolactin .
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Cat. No.: HY-P1520
CAS No.: 215510-22-8
Target:  

GnRH Receptor

Research Areas:  

Neurological Disease

Prolactin Releasing Peptide (1-31), human is a high affinity GPR10 ligand that cause the release of the prolactin. Prolactin Releasing Peptide (1-31) binds to GPR10 for human and rats with Ki values of 1.03 nM and 0.33 nM, respectively. Prolactin Releasing Peptide (1-31) can be used for the research of the hypothalamo-pituitary axis .
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Cat. No.: HY-P1520A
Target:  

GnRH Receptor

Research Areas:  

Neurological Disease

Prolactin Releasing Peptide (1-31), human (acetate) is a high affinity GPR10 ligand that causes the release of the prolactin. Prolactin Releasing Peptide (1-31) binds to GPR10 for human and rats with Ki values of 1.03 nM and 0.33 nM, respectively. Prolactin Releasing Peptide (1-31) can be used for the research of the hypothalamo-pituitary axis .
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Cat. No.: HY-P0246
CAS No.: 72093-21-1
Mastoparan, a tetradecapeptide which is a component of wasp venom, stimulates release of prolactin from cultured rat anterior pituitary cells.
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Cat. No.: HY-13736A
CAS No.: 94424-50-7
Synonyms: CV205-502 hydrochloride
Target:  

Dopamine Receptor Akt

Research Areas:  

Neurological Disease Cancer

Quinagolide hydrochloride (CV205-502 hydrochloride) is a selective and orally active dopamine D2 receptor agonist. Quinagolide hydrochloride is an inhibitor of prolactin. Quinagolide hydrochloride down-regulates AKT levels and its phosphorylation. Quinagolide hydrochloride shows antitumor effects, it can be used for the research of cancer .
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Cat. No.: HY-P99238
CAS No.: 2095467-30-2

Target:  

ADC Antibodies

Research Areas:  

Inflammation/Immunology Cancer

Rolinsatamab is a IgG1κ type chimeric antibody targeting to PRLR (prolactin receptor). Rolinsatamab can be conjugated with pyrrolobenzodiazepine (PDB) dimer SGD-1882 (HY-101127) via a cleavable maleimidocaproyl type linker, to form an antibody-drug conjugate, Rolinsatamab talirine. One Rolinsatamab talirine has an average of 2 site-specific drug attachment engineered cysteines (S239C). The linker equips the valine-alanine dipeptide, as cathepsine B cleavage site. on an average of 2 site-specific drug attachment engineered cysteines (S239C) .
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Cat. No.: HY-101324A
CAS No.: 61655-58-1
Purity:  99.69%
Synonyms: CPP monohydrochloride
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

MK-212 monohydrochloride (CPP monohydrochloride) is an orally active, blood-brain barrier permeable agonist of 5-HT1C, 5-HT2 and 5-HT1A receptors. MK-212 monohydrochloride induces hyperthermia, nausea, arousal, irritability and restlessness, inhibits the elevation of plasma cortisol and prolactin, and reduces feelings of calmness and overall positive affect. MK-212 monohydrochloride mediates anxiety-like behaviors and motor inhibition. MK-212 monohydrochloride is applicable to research related to schizophrenia and anxiety disorders .
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Cat. No.: HY-P3789
CAS No.: 222988-10-5
Target:  

GnRH Receptor

Research Areas:  

Metabolic Disease

Prolactin-Releasing Peptide (12-31), rat is a fragment of the prolactin releasing peptide (PrRP). Prolactin-Releasing Peptide (12-31), rat shows high affinity for GPR10 receptors. Prolactin-Releasing Peptide (12-31), stimulates calcium mobilization in CHOK1 cells transfected with the PrRP receptor .
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Cat. No.: HY-P991358
Synonyms: LFA-102; X213

Research Areas:  

Cancer

XOMA-213 (LFA-102; X213) is a human monoclonal antibody (mAb) targeting the prolactin receptor (PRLR), with a Kd value of 2 nM against the human target. XOMA-213 blocks PRL-induced cell proliferation and inhibits the activation of multiple PRLR ligands, including PRL and human growth hormone (hGH). XOMA-213 suppresses PRL-induced phosphorylation of Stat5, Akt and ERK1/2 in cells. XOMA-213 induces tumor regression, delays disease progression, and inhibits PRLR signaling as well as tumor growth. XOMA-213 can be used in research related to breast cancer .
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Cat. No.: HY-P11341
Target:  

Kisspeptin Receptor

Research Areas:  

Endocrinology

Kisspeptin antagonist p271 is a Kisspeptin antagonist with cell-penetrating ability. Kisspeptin antagonist p271 can block the binding of endogenous Kisspeptin to GPR54 on pituitary somatotropes, thereby relieving the inhibition of growth hormone secretion. Kisspeptin antagonist p271 can specifically and significantly stimulate growth hormone secretion, while inhibiting luteinizing hormone without affecting prolactin or cortisol. Kisspeptin antagonist p271 can be used in the research of diseases related to insufficient growth hormone secretion .
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