1. GPCR/G Protein
    Neuronal Signaling
  2. Dopamine Receptor
  3. Fluphenazine decanoate

Fluphenazine decanoate 

Cat. No.: HY-B1904
Handling Instructions

Fluphenazine decanoate is a long-acting phenothiazine neuroleptic that used to treat schizophrenia. Fluphenazine decanoate is also a high and continuous dopamine D2 receptor blocker.

For research use only. We do not sell to patients.

Fluphenazine decanoate Chemical Structure

Fluphenazine decanoate Chemical Structure

CAS No. : 5002-47-1

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10 mM * 1 mL in DMSO USD 50 In-stock
Estimated Time of Arrival: December 31
10 mg USD 75 In-stock
Estimated Time of Arrival: December 31
50 mg USD 130 In-stock
Estimated Time of Arrival: December 31
100 mg USD 220 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Fluphenazine decanoate is a long-acting phenothiazine neuroleptic that used to treat schizophrenia. Fluphenazine decanoate is also a high and continuous dopamine D2 receptor blocker[1][2][3].

IC50 & Target

Dopamine D2 receptor[2]

In Vivo

Six female Persian onagers (Equus hemionus onager) are treated with Fluphenazine decanoate (0.1 mg/kg IM) or saline control. Urinary cortisol, progesterone, estrogen metabolites and behavior are monitored, and follicular dynamics are examined using ultrasonography until ovulation. Onagers demonstrate significantly lower cortisol concentrations when treated with Fluphenazine decanoate (6.61 ng/mg creatinine) compared to saline (9.73 ng/mg creatinine). There are no differences in peak estrogen or progesterone concentrations between the two groups, and all animals ovulate within the expected time frame following Fluphenazine decanoate treatment. However, some onagers exhibit only minor reductions in cortisol secretion and one treated female demonstrates a suppressed luteal progesterone peak, indicating a possible reproductive cost to Fluphenazine decanoate administration[1].

Molecular Weight

591.77

Formula

C₃₂H₄₄F₃N₃O₂S

CAS No.

5002-47-1

SMILES

CCCCCCCCCC(OCCN1CCN(CCCN2C3=C(C=CC=C3)SC4=CC=C(C(F)(F)F)C=C24)CC1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Fluphenazine decanoateDopamine ReceptorLong-actingphenothiazineneurolepticschizophreniadopamine-D2reproductiveInhibitorinhibitorinhibit

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Fluphenazine decanoate
Cat. No.:
HY-B1904
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