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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
94 Results for "
pyrrolidine
" in MedChemExpress (MCE) Product Catalog:
Products (94)
94 Results for "pyrrolidine" in MCE Product Catalog:
2
2 Cited Publications
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Caspase-3-IN-1 (compound 11b) is a potent Caspase-3 inhibitor, with an IC50 of 14.5 nM .
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1 Cited Publications
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ACP-5862 is a major active, circulating, pyrrolidine ring-opened metabolite of Acalabrutinib with an IC50 of 5.0 nM for Bruton tyrosine kinase (BTK). ACP‐5862 is a weak time‐dependent inactivator of CYP3A4 and CYP2C8. Acalabrutinib is an orally active, irreversible, and highly selective BTK inhibitor, with an IC50 of 3 nM and EC50 of 8 nM .
Cat. No.: HY-145001
Purity: 99.69%
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20-HC-Me-Pyrrolidine (compound AI-3d) is a potent Aster protein inhibitor with IC50s of 0.11 μM, 0.06 μM, and 0.71 μM for Aster-A, Aster-B, and Aster-C, respectively. 20-HC-Me-Pyrrolidine blocks the ability of Asters to bind and transfer cholesterol. 20-HC-Me-Pyrrolidine also inhibits the movement of low-density lipoprotein (LDL) cholesterol to the endoplasmic reticulum (ER) .
Synonyms: (+)-(R)-Proline; (R)-(+)-Proline; (R)-2-Carboxypyrrolidine; (R)-Proline
Category:
Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields
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Cat. No.: HY-W002421
CAS No.: 122536-77-0
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1-Methylpyrrolidine is a methylated pyrrolidine, and cation with thermal-origin negative nonlinear optical (self-defocusing) properties .
Cat. No.: HY-79691
CAS No.: 122536-76-9
Cat. No.: HY-W008129
CAS No.: 2584-71-6
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Cat. No.: HY-W012071
CAS No.: 16652-71-4
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Cat. No.: HY-W012908
CAS No.: 609-36-9
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DL-Proline is a racemic mixture of D-Proline and L-Proline, belonging to cyclic imino acids with a five-membered ring structure. DL-Proline serves as a key structural unit in peptide synthesis. DL-Proline stabilizes β-turn conformations and affects the secondary structure of peptide segments. DL-Proline exhibits biological activities such as regulating peptide segment conformations and enhancing cyclic peptide stability. DL-Proline can be used in research on diseases related to peptide structure and function, including cancer and bacterial infections .
Cat. No.: HY-W248665A
CAS No.: 2616553-35-4
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Thalidomide-pyrrolidine hydrochloride (Compound 18) is an E3 ligase ligand. Thalidomide-pyrrolidine serves as a building block for the synthesis of PROTAC ARD-1676 (HY-156111) .
Cat. No.: HY-W012921
CAS No.: 62937-45-5
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Cat. No.: HY-W008446
CAS No.: 176486-63-8
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Cat. No.: HY-W007880
CAS No.: 22348-32-9
Synonyms: (R)-Diphenylprolinol
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(R)-D2PM ((R)-Diphenylprolinol) is an isomer of the psychoactive substance D2PM and a pyrrolidine analog .
Cat. No.: HY-400708
CAS No.: 2414393-47-6
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(R)-Benzyl 2-cyclopropyl-2-hydroxyacetate can be used in the synthesis of pyrrolidines, a relevant molecule for ADC applications .
Cat. No.: HY-W151297
CAS No.: 193693-66-2
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(3S)-Fmoc-1-pyrrolidine-3-carboxylic acid is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-60256
CAS No.: 72580-54-2
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Cat. No.: HY-40102
CAS No.: 119020-01-8
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
