22348-32-9
22348-32-9
Chemical Structure
(R)-D2PM
Synonym(s): (R)-Diphenylprolinol
- CAS No.: 22348-32-9
- Formula:C17H19NO
- Molecular Weight:253.34
IUPAC Name: (R)-diphenyl(pyrrolidin-2-yl)methanol
InChIKey: OGCGXUGBDJGFFY-MRXNPFEDSA-N
SMILES: OC(C1=CC=CC=C1)(C2=CC=CC=C2)[C@@H]3NCCC3
Biological Activity: (R)-D2PM is a dopamine transporter inhibitor. (R)-D2PM is an isomer of D2PM. (R)-D2PM increases dopamine concentration in the synaptic cleft by inhibiting dopamine reuptake, producing central sympathomimetic effects. (R)-D2PM can be used in studies of acute D2PM toxicity and cardiovascular toxicity[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
(R)-D2PM | 99.93% | (R)-D2PM is a dopamine transporter inhibitor. (R)-D2PM is an isomer of D2PM. (R)-D2PM increases dopamine concentration in the synaptic cleft by inhibiting dopamine reuptake, producing central sympathomimetic effects. (R)-D2PM can be used in studies of acute D2PM toxicity and cardiovascular toxicity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.98
HY-W007880A(R)-D2PM hydrochloride -
Similarity Score 0.79
HY-B0530RAzacyclonol (Standard) -
Similarity Score 0.78
HY-B0530AAzacyclonol hydrochloride -
Similarity Score 0.76
HY-187142α-Cyclohexyl-α-phenylbenzenemethanol -
Similarity Score 0.75
HY-W072274(S)-Desoxy-D2PM hydrochloride -
Similarity Score 0.70
HY-A0270Diphenidol -
Similarity Score 0.70
HY-B1343APridinol -
Similarity Score 0.69
HY-180510BFC220 -
Similarity Score 0.69
HY-A0082RDiphenidol hydrochloride (Standard) -
Explore the MedChemAI to find more analogs
References
- [1]. Inagaki S, et al. Rapid enantiomeric separation and simultaneous determination of phenethylamines by ultra high performance liquid chromatography with fluorescence and mass spectrometric detection: application to the analysis of illicit drugs distributed in the Japanese market and biological samples. Drug testing and analysis. 2012 Dec;4(12):1001-8. [Content Brief]
- [2]. Wood DM, et al. Use and acute toxicity associated with the novel psychoactive substances diphenylprolinol (D2PM) and desoxypipradrol (2-DPMP). Clinical toxicology (Philadelphia, Pa.). 2012 Sep;50(8):727-32. [Content Brief]
- [3]. Lidder S, et al. Cardiovascular toxicity associated with recreational use of diphenylprolinol (diphenyl-2-pyrrolidinemethanol [D2PM]). Journal of medical toxicology : official journal of the American College of Medical Toxicology. 2008 Sep;4(3):167-9. [Content Brief]
