(R)-D2PM hydrochloride
(R)-D2PM hydrochloride is a dopamine transporter inhibitor. (R)-D2PM hydrochloride is an isomer of D2PM. (R)-D2PM hydrochloride increases dopamine concentration in the synaptic cleft by inhibiting dopamine reuptake, producing central sympathomimetic effects. (R)-D2PM hydrochloride can be used in studies of acute D2PM toxicity and cardiovascular toxicity.
For research use only. We do not sell to patients.
- CAS No.: 172152-19-1
- Formula: C17H20ClNO
- Molecular Weight:289.80
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
(R)-D2PM hydrochloride binds the dopamine re-uptake transporter with Kibinding 0.04 μM and inhibits dopamine re-uptake with Kiuptake 0.17 μM, yielding a Kibinding:Kiuptake ratio of 4.25[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 172152-19-1
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Molecular Weight 289.80
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Formula C17H20ClNO
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SMILES
OC(C1=CC=CC=C1)(C2=CC=CC=C2)[C@H]3CCCN3.Cl
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Synonyms
(R)-Diphenylprolinol hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Inagaki S, et al. Rapid enantiomeric separation and simultaneous determination of phenethylamines by ultra high performance liquid chromatography with fluorescence and mass spectrometric detection: application to the analysis of illicit drugs distributed in the Japanese market and biological samples. Drug testing and analysis. 2012 Dec;4(12):1001-8. [Content Brief]
[2]. Wood DM, et al. Use and acute toxicity associated with the novel psychoactive substances diphenylprolinol (D2PM) and desoxypipradrol (2-DPMP). Clinical toxicology (Philadelphia, Pa.). 2012 Sep;50(8):727-32. [Content Brief]
[3]. Lidder S, et al. Cardiovascular toxicity associated with recreational use of diphenylprolinol (diphenyl-2-pyrrolidinemethanol [D2PM]). Journal of medical toxicology : official journal of the American College of Medical Toxicology. 2008 Sep;4(3):167-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(R)-D2PM hydrochloride Related Classifications
HY-W007880A Related Classifications
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