123-56-8
123-56-8
Chemical Structure
Succinimide
- CAS No.: 123-56-8
- Formula:C4H5NO2
- Molecular Weight:99.09
IUPAC Name: pyrrolidine-2,5-dione
InChIKey: KZNICNPSHKQLFF-UHFFFAOYSA-N
SMILES: O=C1NC(CC1)=O
Biological Activity: Succinimide is a modifying agent. Binding of Succinimide to the 5-HT7 receptor induces clathrin-mediated endocytosis. Succinimide-modified liposomes exhibit high cellular uptake. Succinimide can be used in the study of glioblastoma[1][2][3].
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Succinimide | 99.92% | Succinimide is a modifying agent. Binding of Succinimide to the 5-HT7 receptor induces clathrin-mediated endocytosis. Succinimide-modified liposomes exhibit high cellular uptake. Succinimide can be used in the study of glioblastoma. | ||||||||||||||||||||
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Succinimide-15N | 99.0% | Succinimide-15N is the 15N-labeled Succinimide (HY-41877). Succinimide is a modifying agent. Binding of Succinimide to the 5-HT7 receptor induces clathrin-mediated endocytosis. Succinimide-modified liposomes exhibit high cellular uptake. Succinimide can be used in the study of glioblastoma. | ||||||||||||||||||||
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References
- [1]. Jiang Y, et al. Discovery of novel pyrrolidine-2,5-dione scaffold PICK1 PDZ inhibitors as anti-ischemic stroke agents. European journal of medicinal chemistry. 2026 Feb 05;303:118410. [Content Brief]
- [2]. Tilekar K, et al. Synthesis and Biological Evaluation of Pyrazoline and Pyrrolidine-2,5-dione Hybrids as Potential Antitumor Agents. ChemMedChem. 2020 Oct 05;15(19):1813-1825.
- [3]. Lubitz LJ, et al. Elevated Cellular Uptake of Succinimide- and Glucose-Modified Liposomes for Blood-Brain Barrier Transfer and Glioblastoma Therapy. Biomedicines. 2024 Sep 20;12(9):2135.
