123-56-8
123-56-8
Chemical Structure
Succinimide
Synonym(s): pyrrolidine-2,5-dione
- CAS No.: 123-56-8
- Formula:C4H5NO2
- Molecular Weight:99.09
IUPAC Name: pyrrolidine-2,5-dione
InChIKey: KZNICNPSHKQLFF-UHFFFAOYSA-N
SMILES: O=C1NC(CC1)=O
Biological Activity: Succinimide rapidly hydrolyzes into aspartic acid and aspartic acid during the reduction/alkylation process. Succinimide is utilized in the development of antiepileptic agent[1][2].
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Succinimide | 99.92% | Succinimide rapidly hydrolyzes into aspartic acid and aspartic acid during the reduction/alkylation process. Succinimide is utilized in the development of antiepileptic agent. | ||||||||||||||||||||
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Succinimide-15N | 99.0% | Succinimide-15N is the 15N labeled Succinimide. Succinimide rapidly hydrolyzes into aspartic acid and aspartic acid during the reduction/alkylation process. Succinimide is utilized in the development of antiepileptic agent. | ||||||||||||||||||||
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References
- [1]. Chu GC, et al. Accumulation of succinimide in a recombinant monoclonal antibody in mildly acidic buffers under elevated temperatures. Pharm Res. 2007 Jun;24(6):1145-56. [Content Brief]
- [2]. Yan B, et al. Succinimide formation at Asn 55 in the complementarity determining region of a recombinant monoclonal antibody IgG1 heavy chain. J Pharm Sci. 2009 Oct;98(10):3509-21. [Content Brief]
Keywords
