12 Results for "

rabbit ACE

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "rabbit ACE" in MCE Product Catalog:

Cat. No.: HY-23093
CAS No.: 13433-09-5
L-Aspartyl-L-phenylalanine is a metabolite of aspartame that can inhibit angiotensin converting enzyme (ACE) purified from rabbit lungs with a Ki of 11 μM .
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Cat. No.: HY-P3991
CAS No.: 30953-20-9
Research Areas:  

Metabolic Disease

Bradykinin potentiator C is a potent angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 7.1 μM for rabbit lung ACE. Bradykinin potentiator C is a postulated prototype of functional peptide .
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Cat. No.: HY-P2605
CAS No.: 117620-76-5
Research Areas:  

Metabolic Disease

Tuna AI, an angiotensin-converting enzyme (ACE) inhibitor, exhibits IC50 values of 1 μM and 2 μM for ACEs from bovine and rabbit lungs, respectively .
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Cat. No.: HY-131280R
CAS No.: 676129-92-3
Research Areas:  

Others

L-Aspartyl-L-phenylalanine (Standard) is the analytical standard of L-Aspartyl-L-phenylalanine. This product is intended for research and analytical applications. L-Aspartyl-L-phenylalanine is a metabolite of aspartame that can inhibit angiotensin converting enzyme (ACE) purified from rabbit lungs with a Ki of 11 μM .
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Cat. No.: HY-23093R
CAS No.: 13433-09-5
L-Aspartyl-L-phenylalanine (Standard) is the analytical standard of L-Aspartyl-L-phenylalanine. This product is intended for research and analytical applications. L-Aspartyl-L-phenylalanine is a metabolite of aspartame that can inhibit angiotensin converting enzyme (ACE) purified from rabbit lungs with a Ki of 11 μM .
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Cat. No.: HY-105572
CAS No.: 85921-53-5
Synonyms: MC-838 calcium
Moveltipril calcium (MC-838 calcium) is an orally active angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Moveltipril calcium binds via a stable thioester bond and exhibits relative resistance to enzymatic hydrolysis in rat liver homogenate. Moveltipril calcium effectively inhibits ACE extracted from rabbit lung in a concentration-dependent manner. Moveltipril calcium is able to highly specifically inhibit the contractile response to angiotensin-I (AI) in free rat aortic rings and guinea pig ileum preparations, while enhancing the contractile response to calcitonin .
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Cat. No.: HY-P11941
CAS No.: 180341-69-9
Acein-1 is an angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 16 μM against rabbit lung ACE. Acein-1 does not bind to the catalytic site of ACE and cannot be hydrolyzed by ACE. Acein-1 can be used in the research of hypertension .
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Cat. No.: HY-182445
CAS No.: 140369-78-4
FPL 66564 is a short-acting angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 5.7 nM against rabbit ACE. FPL 66564 inhibits ACE activity at the functional level and is hydrolyzed in human blood into inactive hydrophilic metabolites. FPL 66564 modulates angiotensin I-induced pressor responses in anesthetized rats, and its effects rapidly return to baseline after cessation of intravenous infusion. FPL 66564 can be used for research on cardiovascular regulation related to critical illness .
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Cat. No.: HY-182407
CAS No.: 100277-62-1
CV 5975 is an orally active angiotensin converting enzyme (ACE) competitive inhibitor with a rabbit lung ACE IC50 of 3.1 nM and Ki values of 2.6 nM. CV 5975 inhibits ACE in plasma, aorta, kidney, and brain, intensifying inhibition with repeated administration. CV 5975 inhibits Angiotensin I (HY-P1032)-induced pressor responses and ileum contraction, and augments bradykinin-induced ileum contraction and depressor responses. CV 5975 reduces blood pressure via ACE-independent mechanisms, with sustained action across multiple hypertensive and normotensive animal models, intensified by repeated dosing or Hydrochlorothiazide (HY-B0252) co-administration. CV 5975 can be used for the research of hypertension .
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Cat. No.: HY-N19889
CAS No.: 136083-88-0
Plantainoside E is a phenylpropanoid glycoside. Plantainoside E can be isolated from the leaves of Plantago major L. Plantainoside E shows no angiotensin-converting enzyme inhibitory activity. Plantainoside E can be used in hypertension research .
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Cat. No.: HY-103294
CAS No.: 229030-05-1
Target:  

Endogenous Metabolite

Research Areas:  

Others

R892 is a selective and efficient bradyKinin B1 receptor antagonist with significant antagonistic activity. The pA2 values of R892 in human and rabbit B1 receptors are 8.8 and 8.6 respectively, indicating its strong anti-activity at these receptors. R892 exhibits selectivity with ID50 values of 2.8 nM and >600 nM for B1 and B2 receptors, respectively, and has no endogenous agonist activity. R892 is resistant to aminopeptidase and kininase II (ACE) degradation and exhibits metabolic stability .
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Cat. No.: HY-182301
CAS No.: 112227-15-3
Target:  

Renin

Research Areas:  

Cardiovascular Disease

CP 71362 is a renin inhibitor, a highly potent substrate-analog transition state mimic with antihypertensive properties. CP 71362 exhibits significant inhibitory activity against plasma renin from rats, dogs, and humans (IC50 values are 3 nM, 0.0033 nM, and 20 nM, respectively). CP 71362 reduces the mean arterial pressure of anesthetized and conscious sodium-depleted animals in a dose-dependent manner, and has pharmacokinetic characteristics of rapid elimination and short duration of action. CP 71362 can be used in research related to hypertension and congestive heart failure .
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