R892
R892 is a selective and efficient bradyKinin B1 receptor antagonist with significant antagonistic activity. The pA2 values of R892 in human and rabbit B1 receptors are 8.8 and 8.6 respectively, indicating its strong anti-activity at these receptors. R892 exhibits selectivity with ID50 values of 2.8 nM and >600 nM for B1 and B2 receptors, respectively, and has no endogenous agonist activity. R892 is resistant to aminopeptidase and kininase II (ACE) degradation and exhibits metabolic stability.
For research use only. We do not sell to patients.
- CAS No.: 229030-05-1
- Formula: C58H83N13O12
- Molecular Weight:1154.36
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All Endogenous Metabolite Isoforms
More
Biological Activity
Chemical Information
-
CAS No. 229030-05-1
-
Molecular Weight 1154.36
-
Formula C58H83N13O12
-
Sequence
Ac-Lys-Arg-Pro-Pro-Gly-{Phe
}-Ser-{d-Nal}-Ile -
Sequence Shortening
Ac-KRPPG-{Phe
}-SA-{d-Nal}-I -
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
R892 Related Classifications
HY-103294 Related Classifications
Powered by Bioz