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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
succinate dehydrogenase complex
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "succinate dehydrogenase complex" in MCE Product Catalog:
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1 Cited Publications
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1 Cited Publications
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Fluxapyroxad is a synthetic broad-spectrum fungicide for the control of fungal diseases. Fluxapyroxad inhibits succinate dehydrogenase in complex II of the mitochondrial respiratory chain, resulting in inhibition of spore germination, germ tubes and mycelia growth within the fungus target species .
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Penthiopyrad (MTF-753) is a carboxamide Fungicide. Penthiopyrad inhibits SDH. Penthiopyrad exhibits broad-spectrum antifungal activity, being effective not only against Basidiomycetes, but also against Ascomycetes and Deuteromycetes. Penthiopyrad inhibits the mycelial growth of Alternaria mali, Botrytis cinerea, Monilinia mali, Rhizoctonia solani and Sclerotinia sclerotiorum on PDA medium, with EC50 values ranging from <0.4 ppm to 0.34 ppm and MIC values ranging from 6.6 ppm to 47.9 ppm .
Cat. No.: HY-B2011
CAS No.: 66332-96-5
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Flutolanil is a succinate dehydrogenase complex inhibitor and fungicide. Flutolanil blocks electron transfer between the redox center of succinate dehydrogenase and coenzyme Q, inhibits mycelial oxygen consumption, and suppresses mycelial growth. Flutolanil induces acute and sublethal toxicity in zebrafish at different life stages. Flutolanil can be used in studies on plant disease control .
Cat. No.: HY-W516735
CAS No.: 874967-67-6
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Sedaxane is a new broad-spectrum seed treatment fungicide. Sedaxane inhibits fungal respiration by binding to the succinate dehydrogenase complex in fungal mitochondria. Sedaxane has broad-spectrum activity against a variety of seed-borne and soil-borne fungi. Sedaxane can be used in the study of barley loose smut and barley stripe disease .
Cat. No.: HY-19688B
CAS No.: 1019640-33-5
Synonyms: WR 6026 tosylate
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Sitamaquine (WR6026) tosylate, an orally active 8-aminoquinoline analog, is an antileishmanial agent. Sitamaquine tosylate inhibits mitochondrial complex II (succinate dehydrogenase). Sitamaquine tosylate is a lipophilic weak base that rapidly accumulates in acidic compartments of Leishmania spp., mainly in acidocalcisomes .
Cat. No.: HY-124408
CAS No.: 55814-41-0
Mepronil, a compound belonging to the carboxyamine group of fungicides, has a particularly strong bactericidal effect on basidiomycete fungi. Mepronil acts as a single point inhibitor of the succinate ubiquinone reductase or succinate dehydrogenase complex. Mepronil can be used in the study of cross resistance and biological infection .
Cat. No.: HY-B2011R
CAS No.: 66332-96-5
Target:
Reference Standards Fungal Mitochondrial Metabolism Succinate Dehydrogenase Environmental Pollutants
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Flutolanil (Standard) is the analytical standard of Flutolanil (HY-B2011). This product is intended for research and analytical applications. Flutolanil is a succinate dehydrogenase complex inhibitor and fungicide. Flutolanil blocks electron transfer between the redox center of succinate dehydrogenase and coenzyme Q, inhibits mycelial oxygen consumption, and suppresses mycelial growth. Flutolanil induces acute and sublethal toxicity in zebrafish at different life stages. Flutolanil can be used in studies on plant disease control .
Cat. No.: HY-124408R
CAS No.: 55814-41-0
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Mepronil (Standard) is the analytical standard of Mepronil. This product is intended for research and analytical applications. Mepronil, a compound belonging to the carboxyamine group of fungicides, has a particularly strong bactericidal effect on basidiomycete fungi. Mepronil acts as a single point inhibitor of the succinate ubiquinone reductase or succinate dehydrogenase complex. Mepronil can be used in the study of cross resistance and biological infection .
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Sitamaquine (WR6026) hydrochloride, an orally active 8-aminoquinoline analog, is an antileishmanial agent. Sitamaquine hydrochloride inhibits mitochondrial complex II (succinate dehydrogenase). Sitamaquine hydrochloride is a lipophilic weak base that rapidly accumulates in acidic compartments of Leishmania spp., mainly in acidocalcisomes .
Cat. No.: HY-135549R
CAS No.: 907204-31-3
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Fluxapyroxad (Standard) is the analytical standard of Fluxapyroxad. This product is intended for research and analytical applications. Fluxapyroxad is a synthetic broad-spectrum fungicide for the control of fungal diseases. It works by inhibiting succinate dehydrogenase in complex II of the mitochondrial respiratory chain, resulting in inhibition of spore germination, germ tubes and mycelia growth within the fungus target species .
Cat. No.: HY-172777
CAS No.: 3052432-15-9
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SDH-IN-25 is a succinate dehydrogenase (SDH) inhibitor (IC50 = 4.82 mg/L). SDH-IN-25 exhibited broad-spectrum and potent antifungal activity. SDH-IN-25 mimics the interaction pattern of commercial fungicide Fluxapyroxad (HY-135549) through binding to SDH amino acid residues (TRP173, TYR58, and ARG43). SDH-IN-25 can induce hyphal morphology, interfere with respiratory metabolism by binding to complex II, generate reactive oxygen species (ROS), and affect mitochondrial membrane potential (MMP) in mycelia. SDH-IN-25 can be studied in research for agricultural disease control .
Cat. No.: HY-119976S
CAS No.: 2468796-76-9
Cat. No.: HY-119976R
CAS No.: 188425-85-6
Cat. No.: HY-W725177
CAS No.: 1352994-67-2
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Inpyrfluxam is a succinate dehydrogenase (SDH) inhibitor. Inpyrfluxam targets the ubiquinone binding pocket of mitochondrial SDH complex subunits ViSDHB, ViSDHC, ViSDHD, interfering with cellular respiration. Inpyrfluxam inhibits conidial germination and mycelial growth of Venturia inaequalis in vitro. Inpyrfluxam can be used for the research of apple scab .
Cat. No.: HY-182534
CAS No.: 2110408-47-2
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Succinate dehydrogenase-IN-12 is a selective inhibitor of mitochondrial complex II (succinate dehydrogenase), with an IC50 value of 3.3 nM. Succinate dehydrogenase-IN-12 can be used for tumor research .
Cat. No.: HY-P704801
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SDHA; succinate dehydrogenase [Ubiquinone] Flavoprotein Subunit; Prev. SDH2; CMD1GG; SDHF; MC2DN1; succinate dehydrogenase [Ubiquinone] Flavoprotein Subunit, Mitochondrial; NDAXOA; Flavoprotein Subunit Of complex II; PPGL5; FP; PGL5; succinate Dehydrogena
Cat. No.: HY-P87067
Synonyms: CYB560 antibody; C560_HUMAN antibody; CYBL antibody; Cytochrome B large subunit of complex II antibody; Integral membrane protein CII-3 antibody; mitochondrial antibody; PGL3 antibody; QPs-1 antibody; QPs1 antibody; SDH3 antibody; CYB560 antibody; C560_HUMAN antibody; CYBL antibody; Cytochrome B large subunit of complex II antibody; Integral membrane protein CII-3 antibody; mitochondrial antibody; PGL3 antibody; QPs-1 antibody; QPs1 antibody; SDH3 antibody; sdhC antibody; succinate dehydrgenase cytochrome b antibody; succinate dehydrogenase 3, integral membrane subunit antibody; succinate dehydrogenase complex subunit C antibody; succinate dehydrogenase complex subunit C integral membrane protein 15kDa antibody; succinate dehydrogenase cytochrome b560 subunit antibody; succinate dehydrogenase cytochrome b560 subunit mitochondrial antibody; succinate dehydrogenase cytochrome b560 subunit, mitochondrial precursor antibody; succinate-ubiquinone oxidoreductase cytochrome B large subunit antibody;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
