1. Metabolic Enzyme/Protease
  2. Succinate Dehydrogenase
  3. Succinate dehydrogenase-IN-12

Succinate dehydrogenase-IN-12 is a selective inhibitor of mitochondrial complex II (succinate dehydrogenase), with an IC50 value of 3.3 nM. Succinate dehydrogenase-IN-12 can be used for tumor research.

For research use only. We do not sell to patients.

Succinate dehydrogenase-IN-12

Succinate dehydrogenase-IN-12 Chemical Structure

CAS No. : 2110408-47-2

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Description

Succinate dehydrogenase-IN-12 is a selective inhibitor of mitochondrial complex II (succinate dehydrogenase), with an IC50 value of 3.3 nM. Succinate dehydrogenase-IN-12 can be used for tumor research[1].

In Vitro

Succinate dehydrogenase-IN-12 (compound 16k) has IC50 values of 2, 10.7, and 35 μg/mL against 22Rv1, WPMY-1, and HEK 293 cells, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

367.48

Formula

C20H33NO5

CAS No.
SMILES

O=C1NC(OC)=C(C(O)=C1C(CCCCCCCCCCCC)=O)OC

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Succinate dehydrogenase-IN-12
Cat. No.:
HY-182534
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