Search Result
Results for "
suppressant
" in MedChemExpress (MCE) Product Catalog:
5
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-B1716
-
|
L-5-HTP; Oxitriptan
|
Endogenous Metabolite
|
Neurological Disease
Metabolic Disease
|
|
L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist . L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia .
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- HY-Y1282
-
|
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Environmental Pollutants
Biochemical Assay Reagents
SOD
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Cardiovascular Disease
Infection
Neurological Disease
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Sodium tetraborate decahydrate is an orally active biochemical reagent and antibacterial agent. Sodium tetraborate decahydrate leads to an increase in the activity of Catalase, Superoxide dismutase. Sodium tetraborate decahydrate reduces Hydrogen sulfide and the sulfate-reducing bacteria population of swine manure. Sodium tetraborate decahydrate serves as flame suppressant for wood cellulose. Sodium tetraborate decahydrate is a triglyceride transesterification catalyst. Sodium tetraborate decahydrate suppresses the formation of chlorinated by-products in Cl −-containing water. Sodium tetraborate decahydrate has a neuroprotective effect against chromium poisoning. Sodium tetraborate decahydrate can protect the heart from chromium damage at low doses. Sodium tetraborate in a low dose with an isolated application shows an antioxidant effect .
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- HY-114657A
-
|
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Arp2/3 Complex
|
Inflammation/Immunology
Cancer
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Benproperine phosphate is an orally active, potent actin-related protein 2/3 complex subunit 2 (ARPC2) inhibitor. Benproperine phosphate attenuates the actin polymerization rate of action polymerization nucleation by impairing Arp2/3 function. Benproperine phosphate has the potential for a cough suppressant and suppresses cancer cell migration and tumor metastasis .
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- HY-B0372A
-
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SARS-CoV
Autophagy
HIV
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Metabolic Disease
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Bromhexine hydrochloride is a potent and specific TMPRSS2 protease inhibitor with an IC50 of 0.75 μM. Bromhexine hydrochloride can prevent and manage SARS-CoV-2 infection. Bromhexine hydrochloride is an autophagy agonist. Bromhexine hydrochloride is a mucolytic cough suppressant and has the potential for a range of respiratory conditions .
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-
- HY-B1216
-
-
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- HY-P2932
-
|
Cholecystokinin-33(human); CCK-33(human)
|
Cholecystokinin Receptor
|
Metabolic Disease
|
|
Cholecystokinin is a peptide hormone. Cholecystokinin, as a hunger suppressant, inhibits food intake and stimulates the digestion of fat and protein. Cholecystokinin can be used for the research of gastrointestinal system .
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- HY-B1042
-
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SKF-9976 citrate; AF-438 citrate
|
Cytochrome P450
|
Inflammation/Immunology
|
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Oxolamine citrate (SKF-9976 citrate) is an orally active antitussive. Oxolamine citrate can inhibit CYP2B1/2. Oxolamine citrate has anti-inflammatory effects on the respiratory organs of guinea pigs. Oxolamine citrate increases the AUC of Warfarin (HY-B0687) and prolongs its terminal half-life. Oxolamine citrate can be used in respiratory disease research .
|
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- HY-B1716S
-
|
L-5-HTP-d3; Oxitriptan-d3
|
Endogenous Metabolite
|
Neurological Disease
Metabolic Disease
|
|
L-5-Hydroxytryptophan-d3 is the deuterium labeled L-5-Hydroxytryptophan. L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist . L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia .
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-
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- HY-135615A
-
|
N-Desmethylsibutramine hydrochloride
|
Serotonin Transporter
|
Neurological Disease
Metabolic Disease
|
|
Desmethyl Sibutramine hydrochloride, the secondary metabolite of Sibutramine, is an orally active norepinephrine transporter (NET) and serotonin transporter (SERT) inhibitor. Desmethyl Sibutramine hydrochloride can be used in the research of obesity and appetite suppressant .
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- HY-122477
-
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Drug Derivative
|
Neurological Disease
|
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Zylofuramine is a psychomotor stimulant. Zylofuramine can be used in the research related to appetite suppressants and Alzheimer's disease .
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- HY-B2115
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|
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Bacterial
|
Inflammation/Immunology
|
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Sulfogaiacol is a cough suppressant with expectorant properties, and it can be used for research on acute respiratory infections with oral activity .
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- HY-101445R
-
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Reference Standards
Reactive Oxygen Species (ROS)
Ferroptosis
Apoptosis
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Cancer
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Butamirate (citrate) (Standard) is the analytical standard of Butamirate (citrate). This product is intended for research and analytical applications. Butamirate citrate is an orally active cough suppressant that acts centrally through the receptors in the brainstem. Butamirate citrate also reduces the resistance in the airways by inhibiting bronchospasm and anti-inflammatory effect .
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- HY-B1716R
-
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L-5-HTP (Standard); Oxitriptan (Standard)
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Endogenous Metabolite
Reference Standards
|
Neurological Disease
Metabolic Disease
|
|
L-5-Hydroxytryptophan (Standard) is the analytical standard of L-5-Hydroxytryptophan. This product is intended for research and analytical applications. L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist . L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia .
|
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- HY-101480
-
|
|
5-HT Receptor
|
Neurological Disease
|
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Xylamidine is a peripheral 5-HT receptor antagonist used to investigate possible peripheral appetite suppressant effects of 5-hydroxytryptophan (5-HTP) and fenfluramine. In a 1-hour food intake test, xylamidine attenuated the decrease in food intake induced by 5-HT and 5-HTP, but had no effect on fenfluramine, suggesting that the appetite suppressant effect of 5-HTP is mediated in part through peripheral 5-HT receptors. Microstructural analysis revealed that 5-HTP and fenfluramine induced a decrease in food intake rate and a reduction in feeding batch size. Xylamidine reversed the effects of 5-HTP on food intake rate and induced a slight increase in feeding batch size itself, thus, the peripheral effect of 5-HTP appears to be to slow food intake rate. No effect of xylamidine on fenfluramine-induced changes in feeding was observed. The results suggest that the appetite suppressant effects of 5-HTP and fenfluramine are differentiated based on the peripheral effects of 5-HTP. The peripheral effects of 5-HTP are distinct from the previously reported 5-HT-induced decreases in feeding batch size and duration. Possible mechanisms underlying the differences in peripheral effects of 5-HT and 5-HTP are discussed.
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- HY-B1716S2
-
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L-5-HTP-d4; Oxitriptan-d4
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Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
L-5-Hydroxytryptophan-d4 (L-5-HTP-d4; Oxitriptan-d4) is a deuterium labeled L-5-Hydroxytryptophan (HY-B1716). L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist . L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia .
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- HY-10194A
-
|
YM-155 hydrochloride
|
Survivin
Autophagy
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Cancer
|
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Sepantronium hydrochloride (YM-155 hydrochloride) is a novel survivin suppressant with an IC50 of 0.54 nM for the inhibition of survivin promoter activity .
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- HY-W742300
-
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SKF 70230A hydrochloride; SQ 15874 hydrochloride; Pipazetate hydrochloride
|
GABA Receptor
|
Inflammation/Immunology
|
|
Pipazethate (SKF 70230A; SQ 15874) hydrochloride is a potent GABA antagonist. Pipazethate hydrochloride shows antitussive activity and can be used in research in cough suppressant .
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- HY-B0372AR
-
|
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Reference Standards
SARS-CoV
Autophagy
HIV
|
Metabolic Disease
|
|
Bromhexine (hydrochloride) (Standard) is the analytical standard of Bromhexine (hydrochloride). This product is intended for research and analytical applications. Bromhexine hydrochloride is a potent and specific TMPRSS2 protease inhibitor with an IC50 of 0.75 μM. Bromhexine hydrochloride can prevent and manage SARS-CoV-2 infection. Bromhexine hydrochloride is an autophagy agonist. Bromhexine hydrochloride is a mucolytic cough suppressant and has the potential for a range of respiratory conditions .
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- HY-B0372AS
-
|
|
Isotope-Labeled Compounds
SARS-CoV
Autophagy
HIV
|
Metabolic Disease
|
|
Bromhexine-d3 (hydrochloride) is deuterium labeled Bromhexine (hydrochloride). Bromhexine hydrochloride is a potent and specific TMPRSS2 protease inhibitor with an IC50 of 0.75 μM. Bromhexine hydrochloride can prevent and manage SARS-CoV-2 infection. Bromhexine hydrochloride is an autophagy agonist. Bromhexine hydrochloride is a mucolytic cough suppressant and has the potential for a range of respiratory conditions .
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- HY-105733A
-
|
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Others
|
Others
|
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Suxemerid disulfate is a non-narcotic cough suppressant .
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- HY-P2592
-
-
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- HY-123176
-
-
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- HY-135615
-
|
N-Desmethylsibutramine
|
Serotonin Transporter
|
Neurological Disease
Metabolic Disease
|
|
Desmethyl Sibutramine, the secondary metabolite of Sibutramine, is an orally active norepinephrine transporter (NET) and serotonin transporter (SERT) inhibitor. Desmethyl Sibutramine can be used in the research of obesity and appetite suppressant .
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- HY-135615AR
-
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N-Desmethylsibutramine hydrochloride (Standard)
|
Reference Standards
Serotonin Transporter
|
Neurological Disease
Metabolic Disease
|
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Desmethyl Sibutramine (hydrochloride) (Standard) is the analytical standard of Desmethyl Sibutramine (hydrochloride). This product is intended for research and analytical applications. Desmethyl Sibutramine hydrochloride, the secondary metabolite of Sibutramine, is an orally active norepinephrine transporter (NET) and serotonin transporter (SERT) inhibitor. Desmethyl Sibutramine hydrochloride can be used in the research of obesity and appetite suppressant .
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- HY-106873A
-
|
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Drug Derivative
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Others
|
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Nepinalone hydrochloride, an alchilaminate derivative of β-tetralone and an orally active cough suppressant, possesses a non-opioid antitussive activity .
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- HY-113261A
-
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GlyT
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Neurological Disease
|
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(Rac)-Oleoylcarnitine is an endogenous acylcarnitine and a potential noncompetitive inhibitor of glycine transporter 2 (GLYT2) that can be used as a pain suppressant.
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- HY-106873
-
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Drug Derivative
|
Others
|
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Nepinalone, an alchilaminate derivative of β-tetralone and an orally active cough suppressant, possesses a non-opioid antitussive activity .
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-
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- HY-P6176
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-
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- HY-148968
-
|
Carbathion
|
Fungal
|
Infection
|
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Metham sodium (Carbathion) is a broad-spectrum soil microbial suppressant. Metham sodium controls soil-borne pests and weeds. Metham sodium inhibits weed seeds, plant-parasitic nematodes, plant pathogenic fungi and soil insects .
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- HY-B1717
-
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Cytochrome P450
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Inflammation/Immunology
|
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Oxolamine (SKF-9976) is an orally active antitussive. Oxolamine can inhibit CYP2B1/2. Oxolamine has anti-inflammatory effects on the respiratory organs of guinea pigs. Oxolamine increases the AUC of Warfarin (HY-B0687) and prolongs its terminal half-life. Oxolamine can be used in respiratory disease research .
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- HY-B1216R
-
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Reference Standards
Sigma Receptor
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Cardiovascular Disease
Others
Neurological Disease
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Oxeladin (citrate) (Standard) is the analytical standard of Oxeladin (citrate). This product is intended for research and analytical applications. Oxeladin citrate is an orally active and brain-penetrant cough suppressant as well as a selective sigma 1 receptor agonist (Ki = 25 nM). Oxeladin can be used for pulmonary diseases and stroke research .
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- HY-121212R
-
|
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Aminotransferases (Transaminases)
Reference Standards
Others
|
Metabolic Disease
Inflammation/Immunology
|
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Desmethyl Sibutramine (hydrochloride) (Standard) is the analytical standard of Desmethyl Sibutramine (hydrochloride). This product is intended for research and analytical applications. Desmethyl Sibutramine hydrochloride, the secondary metabolite of Sibutramine, is an orally active norepinephrine transporter (NET) and serotonin transporter (SERT) inhibitor. Desmethyl Sibutramine hydrochloride can be used in the research of obesity and appetite suppressant .
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- HY-106018A
-
|
GM 611 fumarate
|
Motilin Receptor
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Others
|
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Mitemcinal fumarate is an oral motilium agonist. Studies in rabbits and dogs have shown that it can promote defecation without causing severe diarrhea, increase stool weight without increasing water content in the rabbit constipation model, and reduce the time to first defecation in dogs. Mitemcinal fumarate may be a constipation suppressant due to its early onset and short duration of action.
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- HY-106018
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GM 611
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Motilin Receptor
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Others
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Mitemcinal (GM 611) is an oral motilin receptor agonist. Studies in rabbits and dogs have shown that it can promote defecation without causing severe diarrhea, increase stool weight without increasing water content in the rabbit constipation model, and reduce the time to first defecation in dogs. Mitemcinal may be a constipation suppressant due to its early onset and short duration of action .
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- HY-11084
-
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Endogenous Metabolite
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Neurological Disease
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SNAP-7941 is a selective antagonist with anxiolytic, antidepressant and appetite suppressant activities. SNAP-7941 showed promising biological activity in initial animal studies. SNAP-7941 targets the melanin concentrating hormone receptor MCH1 and has significant inhibitory potential. SNAP-7941 was shown to inhibit the centrally induced MCH-induced drinking effect in in vivo studies .
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- HY-B1716S1
-
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L-5-HTP-d3-1; Oxitriptan-d3-1
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Endogenous Metabolite
|
Metabolic Disease
|
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L-5-Hydroxytryptophan-d3-1 is the deuterium labeled L-5-Hydroxytryptophan . L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist . L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia .
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- HY-W818693
-
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Apoptosis
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Cancer
|
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3-Hydroxy-3-phenylpentanamide is a compound with neuroprotective activity. 3-Hydroxy-3-phenylpentanamide shows protective effects against ischemic brain injury and cerebral hemorrhage. 3-Hydroxy-3-phenylpentanamide is studied in psychiatry as a potential anxiety, depression and addiction suppressant compound. 3-Hydroxy-3-phenylpentanamide shows antitumor activity in oncology, acting by inducing apoptosis and inhibiting tumor growth. 3-Hydroxy-3-phenylpentanamide also has protective effects against epileptic seizures .
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- HY-117460
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-
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- HY-N9392A
-
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Drug Derivative
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Inflammation/Immunology
|
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Stemospironine is an alkaloid that can be extracted from plants of the genus Hyacinth. Stemospironine is a cough suppressant used to control coughing. Stemospironine can be used for research on inflammatory conditions .
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- HY-B1216A
-
-
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- HY-106873AR
-
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Drug Derivative
Reference Standards
|
Others
|
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Nepinalone hydrochloride (Standard) is the analytical standard of Nepinalone (hydrochloride) (HY-106873A). This product is intended for research and analytical applications. Nepinalone hydrochloride, an alchilaminate derivative of β-tetralone and an orally active cough suppressant, possesses a non-opioid antitussive activity .
|
-
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- HY-B1717A
-
|
|
Cytochrome P450
|
Inflammation/Immunology
|
|
Oxolamine hydrochloride (SKF-9976 hydrochloride) is an orally active antitussive. Oxolamine hydrochloride can inhibit CYP2B1/2. Oxolamine hydrochloride has anti-inflammatory effects on the respiratory organs of guinea pigs. Oxolamine hydrochloride increases the AUC of Warfarin (HY-B0687) and prolongs its terminal half-life. Oxolamine hydrochloride can be used in respiratory disease research .
|
-
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- HY-B1716SA
-
|
L-5-HTP-d3 hydrate; Oxitriptan-d3 hydrate
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Neurological Disease
Metabolic Disease
|
|
L-5-Hydroxytryptophan-d3 (L-5-HTP-d3) hydrate is the deuterium labeled L-5-Hydroxytryptophan (HY-B1716). L-5-Hydroxytryptophan-d3 is the deuterium labeled L-5-Hydroxytryptophan. L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist . L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia .
|
-
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P2932
-
|
Cholecystokinin-33(human); CCK-33(human)
|
Cholecystokinin Receptor
|
Metabolic Disease
|
|
Cholecystokinin is a peptide hormone. Cholecystokinin, as a hunger suppressant, inhibits food intake and stimulates the digestion of fat and protein. Cholecystokinin can be used for the research of gastrointestinal system .
|
-
- HY-P2592
-
-
- HY-P6176
-
-
- HY-P10041
-
|
|
Peptides
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Metabolic Disease
|
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Obestatin(11-23)mouse, rat is a polypeptide involved in regulating energy balance and inhibiting eating. Obestatin(11-23)mouse, rat causes reduced food intake, body weight, and jejunal contractions in rodents .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-B1716S
-
|
|
|
L-5-Hydroxytryptophan-d3 is the deuterium labeled L-5-Hydroxytryptophan. L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist . L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia .
|
-
-
- HY-B1716S2
-
|
|
|
L-5-Hydroxytryptophan-d4 (L-5-HTP-d4; Oxitriptan-d4) is a deuterium labeled L-5-Hydroxytryptophan (HY-B1716). L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist . L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia .
|
-
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- HY-B0372AS
-
|
|
|
Bromhexine-d3 (hydrochloride) is deuterium labeled Bromhexine (hydrochloride). Bromhexine hydrochloride is a potent and specific TMPRSS2 protease inhibitor with an IC50 of 0.75 μM. Bromhexine hydrochloride can prevent and manage SARS-CoV-2 infection. Bromhexine hydrochloride is an autophagy agonist. Bromhexine hydrochloride is a mucolytic cough suppressant and has the potential for a range of respiratory conditions .
|
-
-
- HY-B1716S1
-
|
|
|
L-5-Hydroxytryptophan-d3-1 is the deuterium labeled L-5-Hydroxytryptophan . L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist . L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia .
|
-
-
- HY-B1716SA
-
|
|
|
L-5-Hydroxytryptophan-d3 (L-5-HTP-d3) hydrate is the deuterium labeled L-5-Hydroxytryptophan (HY-B1716). L-5-Hydroxytryptophan-d3 is the deuterium labeled L-5-Hydroxytryptophan. L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist . L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia .
|
-
| Cat. No. |
Product Name |
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Classification |
-
- HY-Y1282
-
|
|
|
Others
|
|
Sodium tetraborate decahydrate is an orally active biochemical reagent and antibacterial agent. Sodium tetraborate decahydrate leads to an increase in the activity of Catalase, Superoxide dismutase. Sodium tetraborate decahydrate reduces Hydrogen sulfide and the sulfate-reducing bacteria population of swine manure. Sodium tetraborate decahydrate serves as flame suppressant for wood cellulose. Sodium tetraborate decahydrate is a triglyceride transesterification catalyst. Sodium tetraborate decahydrate suppresses the formation of chlorinated by-products in Cl −-containing water. Sodium tetraborate decahydrate has a neuroprotective effect against chromium poisoning. Sodium tetraborate decahydrate can protect the heart from chromium damage at low doses. Sodium tetraborate in a low dose with an isolated application shows an antioxidant effect .
|
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