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suppressant

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43

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4

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5

Isotope-Labeled Compounds

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1716
    L-5-Hydroxytryptophan
    3 Publications Verification

    L-5-HTP; Oxitriptan

    Endogenous Metabolite Neurological Disease Metabolic Disease
    L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist . L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia .
    L-5-Hydroxytryptophan
  • HY-Y1282

    Environmental Pollutants Biochemical Assay Reagents SOD Cardiovascular Disease Infection Neurological Disease
    Sodium tetraborate decahydrate is an orally active biochemical reagent and antibacterial agent. Sodium tetraborate decahydrate leads to an increase in the activity of Catalase, Superoxide dismutase. Sodium tetraborate decahydrate reduces Hydrogen sulfide and the sulfate-reducing bacteria population of swine manure. Sodium tetraborate decahydrate serves as flame suppressant for wood cellulose. Sodium tetraborate decahydrate is a triglyceride transesterification catalyst. Sodium tetraborate decahydrate suppresses the formation of chlorinated by-products in Cl -containing water. Sodium tetraborate decahydrate has a neuroprotective effect against chromium poisoning. Sodium tetraborate decahydrate can protect the heart from chromium damage at low doses. Sodium tetraborate in a low dose with an isolated application shows an antioxidant effect .
    Sodium tetraborate decahydrate
  • HY-114657A
    Benproperine phosphate
    2 Publications Verification

    Arp2/3 Complex Inflammation/Immunology Cancer
    Benproperine phosphate is an orally active, potent actin-related protein 2/3 complex subunit 2 (ARPC2) inhibitor. Benproperine phosphate attenuates the actin polymerization rate of action polymerization nucleation by impairing Arp2/3 function. Benproperine phosphate has the potential for a cough suppressant and suppresses cancer cell migration and tumor metastasis .
    Benproperine phosphate
  • HY-B0372A
    Bromhexine hydrochloride
    3 Publications Verification

    SARS-CoV Autophagy HIV Metabolic Disease
    Bromhexine hydrochloride is a potent and specific TMPRSS2 protease inhibitor with an IC50 of 0.75 μM. Bromhexine hydrochloride can prevent and manage SARS-CoV-2 infection. Bromhexine hydrochloride is an autophagy agonist. Bromhexine hydrochloride is a mucolytic cough suppressant and has the potential for a range of respiratory conditions .
    Bromhexine hydrochloride
  • HY-B1216

    Sigma Receptor Cardiovascular Disease Others Neurological Disease
    Oxeladin citrate is an orally active and brain-penetrant cough suppressant as well as a selective sigma 1 receptor agonist (Ki = 25 nM). Oxeladin can be used for pulmonary diseases and stroke research .
    Oxeladin citrate
  • HY-P2932
    Cholecystokinin
    1 Publications Verification

    Cholecystokinin-33(human); CCK-33(human)

    Cholecystokinin Receptor Metabolic Disease
    Cholecystokinin is a peptide hormone. Cholecystokinin, as a hunger suppressant, inhibits food intake and stimulates the digestion of fat and protein. Cholecystokinin can be used for the research of gastrointestinal system .
    Cholecystokinin
  • HY-B1042

    SKF-9976 citrate; AF-438 citrate

    Cytochrome P450 Inflammation/Immunology
    Oxolamine citrate (SKF-9976 citrate) is an orally active antitussive. Oxolamine citrate can inhibit CYP2B1/2. Oxolamine citrate has anti-inflammatory effects on the respiratory organs of guinea pigs. Oxolamine citrate increases the AUC of Warfarin (HY-B0687) and prolongs its terminal half-life. Oxolamine citrate can be used in respiratory disease research .
    Oxolamine citrate
  • HY-B1716S

    L-5-HTP-d3; Oxitriptan-d3

    Endogenous Metabolite Neurological Disease Metabolic Disease
    L-5-Hydroxytryptophan-d3 is the deuterium labeled L-5-Hydroxytryptophan. L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist . L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia .
    L-5-Hydroxytryptophan-d3
  • HY-135615A

    N-Desmethylsibutramine hydrochloride

    Serotonin Transporter Neurological Disease Metabolic Disease
    Desmethyl Sibutramine hydrochloride, the secondary metabolite of Sibutramine, is an orally active norepinephrine transporter (NET) and serotonin transporter (SERT) inhibitor. Desmethyl Sibutramine hydrochloride can be used in the research of obesity and appetite suppressant .
    Desmethyl Sibutramine hydrochloride
  • HY-122477

    Drug Derivative Neurological Disease
    Zylofuramine is a psychomotor stimulant. Zylofuramine can be used in the research related to appetite suppressants and Alzheimer's disease .
    Zylofuramine
  • HY-B2115

    Bacterial Inflammation/Immunology
    Sulfogaiacol is a cough suppressant with expectorant properties, and it can be used for research on acute respiratory infections with oral activity .
    Sulfogaiacol
  • HY-101445R

    Reference Standards Reactive Oxygen Species (ROS) Ferroptosis Apoptosis Cancer
    Butamirate (citrate) (Standard) is the analytical standard of Butamirate (citrate). This product is intended for research and analytical applications. Butamirate citrate is an orally active cough suppressant that acts centrally through the receptors in the brainstem. Butamirate citrate also reduces the resistance in the airways by inhibiting bronchospasm and anti-inflammatory effect .
    Trolox (Standard)
  • HY-B1716R
    L-5-Hydroxytryptophan (Standard)
    3 Publications Verification

    L-5-HTP (Standard); Oxitriptan (Standard)

    Endogenous Metabolite Reference Standards Neurological Disease Metabolic Disease
    L-5-Hydroxytryptophan (Standard) is the analytical standard of L-5-Hydroxytryptophan. This product is intended for research and analytical applications. L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist . L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia .
    L-5-Hydroxytryptophan (Standard)
  • HY-101480

    5-HT Receptor Neurological Disease
    Xylamidine is a peripheral 5-HT receptor antagonist used to investigate possible peripheral appetite suppressant effects of 5-hydroxytryptophan (5-HTP) and fenfluramine. In a 1-hour food intake test, xylamidine attenuated the decrease in food intake induced by 5-HT and 5-HTP, but had no effect on fenfluramine, suggesting that the appetite suppressant effect of 5-HTP is mediated in part through peripheral 5-HT receptors. Microstructural analysis revealed that 5-HTP and fenfluramine induced a decrease in food intake rate and a reduction in feeding batch size. Xylamidine reversed the effects of 5-HTP on food intake rate and induced a slight increase in feeding batch size itself, thus, the peripheral effect of 5-HTP appears to be to slow food intake rate. No effect of xylamidine on fenfluramine-induced changes in feeding was observed. The results suggest that the appetite suppressant effects of 5-HTP and fenfluramine are differentiated based on the peripheral effects of 5-HTP. The peripheral effects of 5-HTP are distinct from the previously reported 5-HT-induced decreases in feeding batch size and duration. Possible mechanisms underlying the differences in peripheral effects of 5-HT and 5-HTP are discussed.
    Xylamidine
  • HY-B1716S2

    L-5-HTP-d4; Oxitriptan-d4

    Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    L-5-Hydroxytryptophan-d4 (L-5-HTP-d4; Oxitriptan-d4) is a deuterium labeled L-5-Hydroxytryptophan (HY-B1716). L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist . L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia .
    L-5-Hydroxytryptophan-d4
  • HY-10194A

    YM-155 hydrochloride

    Survivin Autophagy Cancer
    Sepantronium hydrochloride (YM-155 hydrochloride) is a novel survivin suppressant with an IC50 of 0.54 nM for the inhibition of survivin promoter activity .
    Sepantronium hydrochloride
  • HY-W742300

    SKF 70230A hydrochloride; SQ 15874 hydrochloride; Pipazetate hydrochloride

    GABA Receptor Inflammation/Immunology
    Pipazethate (SKF 70230A; SQ 15874) hydrochloride is a potent GABA antagonist. Pipazethate hydrochloride shows antitussive activity and can be used in research in cough suppressant .
    Pipazethate hydrochloride
  • HY-B0372AR

    Reference Standards SARS-CoV Autophagy HIV Metabolic Disease
    Bromhexine (hydrochloride) (Standard) is the analytical standard of Bromhexine (hydrochloride). This product is intended for research and analytical applications. Bromhexine hydrochloride is a potent and specific TMPRSS2 protease inhibitor with an IC50 of 0.75 μM. Bromhexine hydrochloride can prevent and manage SARS-CoV-2 infection. Bromhexine hydrochloride is an autophagy agonist. Bromhexine hydrochloride is a mucolytic cough suppressant and has the potential for a range of respiratory conditions .
    Bromhexine hydrochloride (Standard)
  • HY-B0372AS

    Isotope-Labeled Compounds SARS-CoV Autophagy HIV Metabolic Disease
    Bromhexine-d3 (hydrochloride) is deuterium labeled Bromhexine (hydrochloride). Bromhexine hydrochloride is a potent and specific TMPRSS2 protease inhibitor with an IC50 of 0.75 μM. Bromhexine hydrochloride can prevent and manage SARS-CoV-2 infection. Bromhexine hydrochloride is an autophagy agonist. Bromhexine hydrochloride is a mucolytic cough suppressant and has the potential for a range of respiratory conditions .
    Bromhexine-d3 hydrochloride
  • HY-105733A

    Others Others
    Suxemerid disulfate is a non-narcotic cough suppressant .
    Suxemerid disulfate
  • HY-P2592

    Cholecystokinin Receptor Others
    Ro 23-7014 is an appetite suppressant. Ro 23-7014 is an analog of cholecystokinin (CCK-7) .
    Ro 23-7014
  • HY-123176

    Orexin Receptor (OX Receptor) Neurological Disease
    GYKI-13380 is an appetite suppressant. GYKI-13380 has the potential for the research of neurology diseases .
    GYKI-13380
  • HY-135615

    N-Desmethylsibutramine

    Serotonin Transporter Neurological Disease Metabolic Disease
    Desmethyl Sibutramine, the secondary metabolite of Sibutramine, is an orally active norepinephrine transporter (NET) and serotonin transporter (SERT) inhibitor. Desmethyl Sibutramine can be used in the research of obesity and appetite suppressant .
    Desmethyl Sibutramine
  • HY-135615AR

    N-Desmethylsibutramine hydrochloride (Standard)

    Reference Standards Serotonin Transporter Neurological Disease Metabolic Disease
    Desmethyl Sibutramine (hydrochloride) (Standard) is the analytical standard of Desmethyl Sibutramine (hydrochloride). This product is intended for research and analytical applications. Desmethyl Sibutramine hydrochloride, the secondary metabolite of Sibutramine, is an orally active norepinephrine transporter (NET) and serotonin transporter (SERT) inhibitor. Desmethyl Sibutramine hydrochloride can be used in the research of obesity and appetite suppressant .
    Desmethyl Sibutramine hydrochloride (Standard)
  • HY-106873A

    Drug Derivative Others
    Nepinalone hydrochloride, an alchilaminate derivative of β-tetralone and an orally active cough suppressant, possesses a non-opioid antitussive activity .
    Nepinalone hydrochloride
  • HY-113261A

    GlyT Neurological Disease
    (Rac)-Oleoylcarnitine is an endogenous acylcarnitine and a potential noncompetitive inhibitor of glycine transporter 2 (GLYT2) that can be used as a pain suppressant.
    (Rac)-Oleoylcarnitine
  • HY-106873

    Drug Derivative Others
    Nepinalone, an alchilaminate derivative of β-tetralone and an orally active cough suppressant, possesses a non-opioid antitussive activity .
    Nepinalone
  • HY-P6176

    Melanocortin Receptor Metabolic Disease Endocrinology
    JLB2-110c activates MCRs receptor (mMC4R EC50 = 0.34 nM) and has a strong in vivo appetite suppressant effect .
    JLB2-110c
  • HY-148968

    Carbathion

    Fungal Infection
    Metham sodium (Carbathion) is a broad-spectrum soil microbial suppressant. Metham sodium controls soil-borne pests and weeds. Metham sodium inhibits weed seeds, plant-parasitic nematodes, plant pathogenic fungi and soil insects .
    Metham sodium
  • HY-B1717

    Cytochrome P450 Inflammation/Immunology
    Oxolamine (SKF-9976) is an orally active antitussive. Oxolamine can inhibit CYP2B1/2. Oxolamine has anti-inflammatory effects on the respiratory organs of guinea pigs. Oxolamine increases the AUC of Warfarin (HY-B0687) and prolongs its terminal half-life. Oxolamine can be used in respiratory disease research .
    Oxolamine
  • HY-B1216R

    Reference Standards Sigma Receptor Cardiovascular Disease Others Neurological Disease
    Oxeladin (citrate) (Standard) is the analytical standard of Oxeladin (citrate). This product is intended for research and analytical applications. Oxeladin citrate is an orally active and brain-penetrant cough suppressant as well as a selective sigma 1 receptor agonist (Ki = 25 nM). Oxeladin can be used for pulmonary diseases and stroke research .
    Oxeladin citrate (Standard)
  • HY-121212R

    Aminotransferases (Transaminases) Reference Standards Others Metabolic Disease Inflammation/Immunology
    Desmethyl Sibutramine (hydrochloride) (Standard) is the analytical standard of Desmethyl Sibutramine (hydrochloride). This product is intended for research and analytical applications. Desmethyl Sibutramine hydrochloride, the secondary metabolite of Sibutramine, is an orally active norepinephrine transporter (NET) and serotonin transporter (SERT) inhibitor. Desmethyl Sibutramine hydrochloride can be used in the research of obesity and appetite suppressant .
    Icosabutate (Standard)
  • HY-106018A

    GM 611 fumarate

    Motilin Receptor Others
    Mitemcinal fumarate is an oral motilium agonist. Studies in rabbits and dogs have shown that it can promote defecation without causing severe diarrhea, increase stool weight without increasing water content in the rabbit constipation model, and reduce the time to first defecation in dogs. Mitemcinal fumarate may be a constipation suppressant due to its early onset and short duration of action.
    Mitemcinal fumarate
  • HY-106018

    GM 611

    Motilin Receptor Others
    Mitemcinal (GM 611) is an oral motilin receptor agonist. Studies in rabbits and dogs have shown that it can promote defecation without causing severe diarrhea, increase stool weight without increasing water content in the rabbit constipation model, and reduce the time to first defecation in dogs. Mitemcinal may be a constipation suppressant due to its early onset and short duration of action .
    Mitemcinal
  • HY-11084

    Endogenous Metabolite Neurological Disease
    SNAP-7941 is a selective antagonist with anxiolytic, antidepressant and appetite suppressant activities. SNAP-7941 showed promising biological activity in initial animal studies. SNAP-7941 targets the melanin concentrating hormone receptor MCH1 and has significant inhibitory potential. SNAP-7941 was shown to inhibit the centrally induced MCH-induced drinking effect in in vivo studies .
    SNAP-7941
  • HY-B1716S1

    L-5-HTP-d3-1; Oxitriptan-d3-1

    Endogenous Metabolite Metabolic Disease
    L-5-Hydroxytryptophan-d3-1 is the deuterium labeled L-5-Hydroxytryptophan . L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist . L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia .
    L-5-Hydroxytryptophan-d3-1
  • HY-W818693

    Apoptosis Cancer
    3-Hydroxy-3-phenylpentanamide is a compound with neuroprotective activity. 3-Hydroxy-3-phenylpentanamide shows protective effects against ischemic brain injury and cerebral hemorrhage. 3-Hydroxy-3-phenylpentanamide is studied in psychiatry as a potential anxiety, depression and addiction suppressant compound. 3-Hydroxy-3-phenylpentanamide shows antitumor activity in oncology, acting by inducing apoptosis and inhibiting tumor growth. 3-Hydroxy-3-phenylpentanamide also has protective effects against epileptic seizures .
    3-Hydroxy-3-phenylpentanamide
  • HY-117460

    Biochemical Assay Reagents Others
    Indanorex is a stimulant agent with appetite suppressant effects and antihyperglycemic effects .
    Indanorex
  • HY-N9392A

    Drug Derivative Inflammation/Immunology
    Stemospironine is an alkaloid that can be extracted from plants of the genus Hyacinth. Stemospironine is a cough suppressant used to control coughing. Stemospironine can be used for research on inflammatory conditions .
    Stemospironine
  • HY-B1216A

    Sigma Receptor Cardiovascular Disease Neurological Disease Inflammation/Immunology
    Oxeladin is an orally active and brain-penetrant cough suppressant as well as a selective sigma 1 receptor agonist (Ki = 25 nM). Oxeladin can be used for pulmonary diseases and stroke research .
    Oxeladin
  • HY-106873AR

    Drug Derivative Reference Standards Others
    Nepinalone hydrochloride (Standard) is the analytical standard of Nepinalone (hydrochloride) (HY-106873A). This product is intended for research and analytical applications. Nepinalone hydrochloride, an alchilaminate derivative of β-tetralone and an orally active cough suppressant, possesses a non-opioid antitussive activity .
    Nepinalone hydrochloride (Standard)
  • HY-B1717A

    Cytochrome P450 Inflammation/Immunology
    Oxolamine hydrochloride (SKF-9976 hydrochloride) is an orally active antitussive. Oxolamine hydrochloride can inhibit CYP2B1/2. Oxolamine hydrochloride has anti-inflammatory effects on the respiratory organs of guinea pigs. Oxolamine hydrochloride increases the AUC of Warfarin (HY-B0687) and prolongs its terminal half-life. Oxolamine hydrochloride can be used in respiratory disease research .
    Oxolamine hydrochloride
  • HY-B1716SA

    L-5-HTP-d3 hydrate; Oxitriptan-d3 hydrate

    Isotope-Labeled Compounds Endogenous Metabolite Neurological Disease Metabolic Disease
    L-5-Hydroxytryptophan-d3 (L-5-HTP-d3) hydrate is the deuterium labeled L-5-Hydroxytryptophan (HY-B1716). L-5-Hydroxytryptophan-d3 is the deuterium labeled L-5-Hydroxytryptophan. L-5-Hydroxytryptophan (L-5-HTP), a naturally occurring amino acid and a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid, is the immediate precursor of the neurotransmitter serotonin and a reserpine antagonist . L-5-Hydroxytryptophan (L-5-HTP) is used to treat fibromyalgia, myoclonus, migraine, and cerebellar ataxia .
    L-5-Hydroxytryptophan-d3 hydrate

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