6056-11-7
6056-11-7
Chemical Structure
Pipazethate hydrochloride
Synonym(s): SKF 70230A hydrochloride; SQ 15874 hydrochloride; Pipazetate hydrochloride
- CAS No.: 6056-11-7
- Formula:C21H26ClN3O3S
- Molecular Weight:435.97
IUPAC Name: 2-(2-(piperidin-1-yl)ethoxy)ethyl 10H-benzo[b]pyrido[2,3-e][1,4]thiazine-10-carboxylate hydrochloride
InChIKey: FEUBUXUFKHXRKO-UHFFFAOYSA-N
SMILES: O=C(N1C2=CC=CC=C2SC3=C1N=CC=C3)OCCOCCN4CCCCC4.Cl
Biological Activity: Pipazethate (SKF 70230A; SQ 15874) hydrochloride is a potent GABA antagonist. Pipazethate hydrochloride shows antitussive activity and can be used in research in cough suppressant [1][2].
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Pipazethate hydrochloride | Pipazethate (SKF 70230A; SQ 15874) hydrochloride is a potent GABA antagonist. Pipazethate hydrochloride shows antitussive activity and can be used in research in cough suppressant . | |||||||||||||||||||||
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References
- [1]. Squires RF, et al. Antidepressants and metabolites that block GABAA receptors coupled to 35S-t-butylbicyclophosphorothionate binding sites in rat brain. Brain Res. 1988 Feb 16;441(1-2):15-22. doi: 10.1016/0006-8993(88)91378-9. [Content Brief]
- [2]. Vakil BJ, et al. Trial of pipazethate as an antitussive. Clin Pharmacol Ther. 1966 Jul-Aug;7(4):515-9. [Content Brief]
Keywords
