7 Results for "

sustained-release agent

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "sustained-release agent" in MCE Product Catalog:

Glycerol dioleate
Glycerol dioleate
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製品番号: HY-154487
CAS 番号: 25637-84-7
Target:  

Biochemical Assay Reagents

研究分野:  

Neurological Disease

Glycerol dioleate is a lipid capable of forming Lyotropic Liquid Crystal (LLC). When formulated with phosphatidylcholine and exposed to aqueous media, glycerol dioleate constructs an inverted hexagonal (HII) phase structure with sustained-release properties. The in-situ forming gel prepared by optimizing glycerol dioleate with phosphatidylcholine and N-methyl-2-pyrrolidone enables stable release of Risperidone (HY-11018) for up to 60 days in vitro and in vivo. Glycerol dioleate causes minimal side effects in rabbits, making it an ideal carrier component for the development of antischizophrenia agents .Note: Lyotropic liquid crystals (Lyotropic Liquid Crystal, LLC) are ordered fluid phases self-assembled by amphipathic molecules (e.g., lipids, surfactants) in solvents (usually water) at specific concentrations .
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Morantel tartrate
Morantel tartrate
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製品番号: HY-B1073
CAS 番号: 26155-31-7
Target:  

Parasite

研究分野:  

Infection

Morantel tartrate is an anthelmintic agent. Sustained-release three-layer composite tablets of Morantel tartrate are administered orally and release after exposure to rumen fluid. Morantel tartrate reduces the fecal egg output and worm burden of gastrointestinal nematodes in Hereford calves. Morantel tartrate is used in research related to gastrointestinal nematode infections .
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PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization)
PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization)
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製品番号: HY-Y0850U5
CAS 番号: 9002-89-5
別名: Polyvinyl alcohol (Mw 27000, 98-99% hydrolyzed, ~600 polymerization); Poly(Ethenol) (Mw 27000, 98-99% hydrolyzed, ~600 polymerization)
PVA (Polyvinyl alcohol) (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) is a nonionic ethanol homopolymer with hydrophilicity, water solubility and biodegradability. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) exhibits biocompatibility, non-toxicity and non-carcinogenicity, as well as antibacterial activity against Gram-positive bacteria, Gram-negative bacteria and fungal strains. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) can serve as a solubilizer, stabilizer, mucoadhesive agent and sustained-release agent, and has a synergistic solubilizing effect on voriconazole/sulfobutyl ether β-cyclodextrin complexes. By stabilizing such complexes, PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) forms freeze-thaw hydrogels with high mucoadhesion, sustained drug release and ex vivo corneal permeability. When compounded with hyaluronic acid hydrogels, PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) supports chondrocyte growth in vitro, and also forms complexes with Cu 2+, Co 2+, Ni 2+ and Zn 2+ ions. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) can be used in studies related to fungal keratitis, bacterial infections and fungal infections .
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PVA (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization)
PVA (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization)
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製品番号: HY-Y0850U2
CAS 番号: 9002-89-5
別名: Polyvinyl alcohol (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization); Poly(Ethenol) (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization)
PVA (Polyvinyl alcohol; Poly(Ethenol)) (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization) is a non-toxic, biodegradable, and highly biocompatible semicrystalline synthetic polymer. PVA (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization) acts as a coating agent to improve tableting performance, and can be cross-linked with sodium trimetaphosphate to prepare tubular vascular grafts or form hydrogels for use as artificial articular cartilage and sustained-release matrices for growth factors. PVA (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization) enhances the redox cycle of iron species in photo-assisted Fenton reactions to simultaneously generate hydrogen peroxide and degrade pollutants, enabling integrated sustainable waste management and water treatment. PVA (Mw 130000, 87-89% hydrolyzed, ~2700 polymerization) is used in the manufacture of biodegradable films and in studies of dry or minimally invasive ex vivo wounds, but cannot form freeze-thaw cross-linked solid sheets for wound dressings .
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Ethyl cellulose (viscosity 10 cP)
Ethyl cellulose (viscosity 10 cP)
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製品番号: HY-W115746A
CAS 番号: 9004-57-3
Ethyl cellulose (viscosity 10 cP) is a non-toxic, biodegradable polymer with unique properties such as oleogel formation, active ingredient delivery, and film-forming ability in the food and pharmaceutical fields. Ethyl cellulose (viscosity 10 cP) can serve as a pharmaceutical excipient, including as a coating agent, flavoring agent, and tablet filler .
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Osimertinib (GMP)
Osimertinib (GMP)
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製品番号: HY-15772G
CAS 番号: 1421373-65-0
別名: AZD-9291 (GMP); Mereletinib (GMP)
Osimertinib (AZD-9291; Mereletinib) GMP is the GMP level of Osimertinib (HY-15772). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. Osimertinib GMP is an inhibitor that selectively targets EGFR T790M and activated EGFR mutants. Osimertinib GMP exerts multiple anti-tumor mechanisms, including radiosensitization, induction of apoptosis and ferroptosis, as well as inhibition of cancer stemness. Osimertinib GMP suppresses EGFR nuclear translocation and downstream survival signaling pathways, significantly reduces cell viability and lipid droplet content, and also exerts synergistic effects with radiotherapy or specific targeted agents to effectively overcome drug resistance and radioresistance. Formulations of Osimertinib GMP modified with liposomes or iRGD enable sustained release, tumor-specific accumulation, and breakthrough of the blood-brain barrier limitation. Osimertinib GMP can be used in research related to radioresistant glioblastoma and non-small cell lung cancer .
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Osimertinib (GMP Like)
Osimertinib (GMP Like)
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製品番号: HY-15772GL
CAS 番号: 1421373-65-0
別名: AZD-9291 (GMP Like); Mereletinib (GMP Like)
Osimertinib (AZD-9291; Mereletinib) GMP Like is the GMP Like level of Osimertinib (HY-15772). GMP Like small molecules works appropriately as an auxiliary reagent for cell research manufacture. Osimertinib GMP Like is an inhibitor that selectively targets EGFR T790M and activated EGFR mutants. Osimertinib GMP Like exerts multiple anti-tumor mechanisms, including radiosensitization, induction of apoptosis and ferroptosis, as well as inhibition of cancer stemness. Osimertinib GMP Like suppresses EGFR nuclear translocation and downstream survival signaling pathways, significantly reduces cell viability and lipid droplet content, and also exerts synergistic effects with radiotherapy or specific targeted agents to effectively overcome drug resistance and radioresistance. Formulations of Osimertinib GMP Like modified with liposomes or iRGD enable sustained release, tumor-specific accumulation, and breakthrough of the blood-brain barrier limitation. Osimertinib GMP Like can be used in research related to radioresistant glioblastoma and non-small cell lung cancer .
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