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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
Betulinic acid
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "Betulinic acid" in MCE Product Catalog:
38
38 Publications Verification
Synonyms: Lupatic acid; Betulic acid
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Cat. No.: HY-W744739
Synonyms: Lupatic acid-d3; Betulic acid-d3
Cat. No.: HY-N3361
CAS No.: 163060-07-9
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NVX-207, a Betulinic acid-derived anti-cancer compound, shows anti-tumor activity (mean IC50=3.5 μM) against various human and canine cell lines. NVX-207-induced apoptosis is associated with activation of the intrinsic apoptotic pathway via cleavage of caspases -9, -3, -7 and of PARP .
Cat. No.: HY-149547
CAS No.: 905838-14-4
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DRF-4015 (Compound 22) is a betulinic acid derivative with antitumor activity .
Cat. No.: HY-155542
CAS No.: 3049676-15-2
RORγ antagonist 1 (compound 22), a potent betulinic acid derivative, is an antagonist of RORγ (KD=0.18 μM). RORγ antagonist 1 exhibits anti-proliferative activity in HPAF-II pancreatic cancer xenograft model. RORγ antagonist 1 inhibits RAS/MAPK and AKT/mTORC1 pathway, and induces caspase-dependent apoptosis in pancreatic cancer cells .
Cat. No.: HY-115720
CAS No.: 2708127-92-6
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Betulinic acid derivative-1 exhibits distinguished activities on inhibiting osteoclast (OC) differentiation with an IC50 value of 1.86 μM.
Cat. No.: HY-N9477
CAS No.: 25613-12-1
Synonyms: Betulin-28-oxime
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Cat. No.: HY-169479
CAS No.: 174740-40-0
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Betulinic glycine amide (compound 5a) is a pentacyclic triterpenoid and derivative of Betulinic acid (HY-10529). Betulinic glycine amide has been used as a precursor in the synthesis of betulinic acid derivatives with anticancer and antiviral activity .
Cat. No.: HY-146338
CAS No.: 150840-75-8
RPR103611, the betulinic acid derivative, is a potent HIV-1 entry inhibitor with IC50s of 80, 0.27, and 0.17 for CCR5-tropic virus YU2, CXCR4-tropic virus NL4-3 and dual tropic virus 89.6, respectively .
Cat. No.: HY-186162
CAS No.: 192211-42-0
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Betulinic acid-OBn is a derivative of Betulinic acid (HY-10529) .
Cat. No.: HY-186162A
CAS No.: 1809996-96-0
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(R)-Betulinic acid-OBn is an isomer of Betulinic acid-OBn(HY-186162) .
Cat. No.: HY-177050
CAS No.: 1199222-56-4
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RG-239 is an orally active TGR5 agonist with an EC50 of 120 nM, significantly outperforming Betulinic acid (HY-10529) (EC50 = 1.04 μM). RG-239 demonstrates higher selectivity for TGR5 compared to the FXRα. RG-239 increases mitochondrial activity in adipocytes and promotes neurite outgrowth at higher concentrations. RG-239 inhibits LPS (HY-D1056)-induced iNOS expression and nitrite production in Raw264.7 and microglia cells. RG-239 can be used for the study of type 2 diabetes [1][2][3][4][5].
Cat. No.: HY-E71272
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β-Amyrin 28-monooxygenase (EC 1.14.13.201), found in plants, is involved in the biosynthesis of oleanane-type triterpenoids, such as ginsenoside Ro. The enzyme from Medicago trunculata (CYP716A12) can also convert α-amyrin and lupeol to ursolic acid and betulinic acid, respectively.
Cat. No.: HY-101597R
CAS No.: 745020-66-0
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NVX-207 (Standard) is the analytical standard of NVX-207 (HY-101597). This product is intended for research and analytical applications. NVX-207, a Betulinic acid-derived anti-cancer compound, shows anti-tumor activity (mean IC50=3.5 μM) against various human and canine cell lines. NVX-207-induced apoptosis is associated with activation of the intrinsic apoptotic pathway via cleavage of caspases -9, -3, -7 and of PARP .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
