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  3. Bacterial
  4. Betulinaldehyde

Betulinaldehyde  (Synonyms: Betulinic aldehyde; Betunal)

Cat. No.: HY-N0084 Purity: 98.72%
COA Handling Instructions

Betulinaldehyde(Betunal) belongs to pentacyclic triterpenoids and was reported to exhibit antimicrobial activities against bacteria and fungi, including S.

For research use only. We do not sell to patients.

Betulinaldehyde Chemical Structure

Betulinaldehyde Chemical Structure

CAS No. : 13159-28-9

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 122 In-stock
Solution
10 mM * 1 mL in DMSO USD 122 In-stock
Solid
5 mg USD 111 In-stock
10 mg USD 178 In-stock
50 mg USD 721 In-stock
100 mg USD 1141 In-stock
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Based on 7 publication(s) in Google Scholar

Betulinaldehyde Related Antibodies

Top Publications Citing Use of Products

    Betulinaldehyde purchased from MedChemExpress. Usage Cited in: Sci Rep. 2023 Jan 13;13(1):743.  [Abstract]

    The positive colony number of A549 cells is reduced by Betulinaldehyde concentrations of > 20 μM, while the colony formation ability of the A549 cells is almost completely inhibited when the concentration reaches 80 μM.

    Betulinaldehyde purchased from MedChemExpress. Usage Cited in: Sci Rep. 2023 Jan 13;13(1):743.  [Abstract]

    Betulinaldehyde (20 μM) for 60 min, the phosphorylated Akt level is significantly inhibited, while the activity of the Akt signaling pathway is almost completely inhibited after 180 min.

    Betulinaldehyde purchased from MedChemExpress. Usage Cited in: Sci Rep. 2023 Jan 13;13(1):743.  [Abstract]

    Betulinaldehyde (20, 40, 80 μM; 24 h) significantly inhibits viability of A549 cells.

    • Biological Activity

    • Purity & Documentation

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    • Customer Review

    Description

    Betulinaldehyde(Betunal) belongs to pentacyclic triterpenoids and was reported to exhibit antimicrobial activities against bacteria and fungi, including S. aureus. IC50 value: Target: Betulinaldehyde(Betunal) belongs to pentacyclic triterpenoids that are based on a 30-carbon skeleton comprising four six-membered rings and one five-membered ring. Betulinaldehyde regulates multiple desirable targets which could be further explored in the development of therapeutic agents for the treatment of S. aureus infections [1]. Study compounds α-amyrin [3β-hydroxy-urs-12-en-3-ol (AM)], betulinic acid [3β-hydroxy-20(29)-lupaene-28-oic acid (BA)] and betulinaldehyde [3β-hydroxy-20(29)-lupen-28-al (BE)] belong to pentacyclic triterpenoids and were reported to exhibit antimicrobial activities against bacteria and fungi, including S. aureus. The MIC values of these compounds against a reference strain of methicillin-resistant S. aureus (MRSA) (ATCC 43300) ranged from 64 μg/ml to 512 μg/ml. However, the response mechanisms of S. aureus to these compounds are still poorly understood [2].

    Molecular Weight

    440.70

    Appearance

    Solid

    Formula

    C30H48O2
    CAS No.
    SMILES

    C=C(C)[C@@H]1CC[C@]2(C=O)CC[C@@]3(C)[C@]4(C)CC[C@@]5([H])C(C)(C)[C@@H](O)CC[C@]5(C)[C@@]4([H])CC[C@]3([H])[C@]21[H]
    Structure Classification
    Initial Source
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage
    Powder -20°C 3 years
    4°C 2 years
    In solvent -80°C 2 years
    -20°C 1 year
    Solvent & Solubility
    In Vitro: 

    DMSO : 20 mg/mL (45.38 mM; Need ultrasonic)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 2.2691 mL 11.3456 mL 22.6912 mL
    5 mM 0.4538 mL 2.2691 mL 4.5382 mL
    10 mM 0.2269 mL 1.1346 mL 2.2691 mL
    *Please refer to the solubility information to select the appropriate solvent.
    In Vivo:
    • 1.

      Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

      Solubility: ≥ 2 mg/mL (4.54 mM); Clear solution

    • 2.

      Add each solvent one by one:  10% DMSO    90% Corn Oil

      Solubility: ≥ 2 mg/mL (4.54 mM); Clear solution

    *All of the co-solvents are available by MedChemExpress (MCE).
    Purity & Documentation

    Purity: 98.72%

    COA (253 KB) RP-HPLC (218 KB)

    Handling Instructions (2659 KB)
    References
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    Betulinaldehyde Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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    This equation is commonly abbreviated as: C1V1 = C2V2

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    × = ×
    C1   V1   C2   V2

    Keywords:

    Betulinaldehyde13159-28-9Betulinic aldehyde BetunalBacterialInhibitorinhibitorinhibit

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