15761-38-3
Chemical Structure
Boc-L-Ala-OH
Synonym(s): Boc-Ala-OH
- CAS No.: 15761-38-3
- Formula:C8H15NO4
- Molecular Weight:189.21
IUPAC Name: (tert-butoxycarbonyl)-L-alanine
InChIKey: QVHJQCGUWFKTSE-YFKPBYRVSA-N
SMILES: OC([C@H](C)NC(OC(C)(C)C)=O)=O
Biological Activity: Boc-L-Ala-OH (Boc-Ala-OH) is a single N-protected amino acid ligand and a protected L-alanine derivative. Boc-L-Ala-OH promotes Pd (II)-catalyzed enantioselective C-H alkenylation and kinetic resolution. Boc-L-Ala-OH serves as a coupling reagent for the synthesis of liver-targeted glycogen phosphorylase inhibitors and P6A metabolites, and also acts as a negative control in synthesis studies of betulinic acid amino acid esters. Boc-L-Ala-OH is applicable to research on epidermoid squamous cell carcinoma[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Boc-L-Ala-OH | 99.07% | Boc-L-Ala-OH (Boc-Ala-OH) is a single N-protected amino acid ligand and a protected L-alanine derivative. Boc-L-Ala-OH promotes Pd (II)-catalyzed enantioselective C-H alkenylation and kinetic resolution. Boc-L-Ala-OH serves as a coupling reagent for the synthesis of liver-targeted glycogen phosphorylase inhibitors and P6A metabolites, and also acts as a negative control in synthesis studies of betulinic acid amino acid esters. Boc-L-Ala-OH is applicable to research on epidermoid squamous cell carcinoma. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Boc-L-Ala-OH-d4 | Boc-L-Ala-OH-d4 is the deuterium labeled Boc-L-Ala-OH. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Boc-L-Ala-OH-d3 | Boc-L-Ala-OH-d3 is the deuterium labeled Boc-L-Ala-OH. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Boc-Ala-OH-1-13C | 99.0% | Boc-Ala-OH-1-13C is the 13C labeled Boc-Ala-OH. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Boc-L-Ala-OH-3-13C | Boc-L-Ala-OH-3-13C is a 13C-labeled Boc-L-Ala-OH (HY-41121). Boc-L-Ala-OH (Boc-Ala-OH) shows excellent affinity with ATP. Boc-L-Ala-OH contains an amino acid moiety, and an acylamide bond like that of the peptide and protein. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Boc-L-Ala-OH-15N | Boc-L-Ala-OH-15N is the 15N labeled Boc-L-Ala-OH. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Boc-L-Ala-OH-d | Boc-L-Ala-OH-d is the deuterium labeled Boc-L-Ala-OH. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Boc-L-Ala-OH-2-13C | Boc-L-Ala-OH-2-13C is a 13C-labeled Boc-L-Ala-OH (HY-41121). Boc-L-Ala-OH (Boc-Ala-OH) shows excellent affinity with ATP. Boc-L-Ala-OH contains an amino acid moiety, and an acylamide bond like that of the peptide and protein. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Xiao K J, et al. Enantioselective C− H Olefination of α‐Hydroxy and α‐Amino Phenylacetic Acids by Kinetic Resolution[J]. Angewandte Chemie International Edition, 2016, 55(8): 2856-2860.
- [2]. Drąg-Zalesińska M, et al. The new esters derivatives of betulin and betulinic acid in epidermoid squamous carcinoma treatment - In vitro studies. Biomed Pharmacother. 2015;72:91-97. [Content Brief]
- [3]. Zhang L, et al. Novel Liver-targeted conjugates of Glycogen Phosphorylase Inhibitor PSN-357 for the Treatment of Diabetes: Design, Synthesis, Pharmacokinetic and Pharmacological Evaluations. Sci Rep. 2017;7:42251. Published 2017 Feb 22. [Content Brief]
- [4]. Zhao M, et al. Identification, synthesis and bioassay for the metabolites of P6A. Bioorg Med Chem. 2003;11(23):4913-4920. [Content Brief]
