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  3. Drug Derivative
  4. DRF-4015

DRF-4015 (Compound 22) is a betulinic acid derivative with antitumor activity.

For research use only. We do not sell to patients.

DRF-4015

DRF-4015 Chemical Structure

CAS No. : 905838-14-4

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Based on 1 publication(s) in Google Scholar

DRF-4015 Related Antibodies

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Description

DRF-4015 (Compound 22) is a betulinic acid derivative with antitumor activity[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
3.53 μg/mL
Compound: 38
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
[PMID: 18752941]
DU-145 IC50
7 μg/mL
Compound: 38
Cytotoxicity against human DU145 cells after 72 hrs by MTT assay
Cytotoxicity against human DU145 cells after 72 hrs by MTT assay
[PMID: 18752941]
HBL-100 IC50
> 20 μg/mL
Compound: 38
Cytotoxicity against human HBL100 cells after 72 hrs by MTT assay
Cytotoxicity against human HBL100 cells after 72 hrs by MTT assay
[PMID: 18752941]
K562 IC50
11.92 μg/mL
Compound: 38
Cytotoxicity against human K-562 cells after 72 hrs by MTT assay
Cytotoxicity against human K-562 cells after 72 hrs by MTT assay
[PMID: 18752941]
MIA PaCa-2 IC50
0.67 μg/mL
Compound: 38
Cytotoxicity against human MIA PaCa2 cells after 72 hrs by MTT assay
Cytotoxicity against human MIA PaCa2 cells after 72 hrs by MTT assay
[PMID: 18752941]
NIH3T3 IC50
0.68 μg/mL
Compound: 38
Cytotoxicity against mouse NIH3T3 cells after 72 hrs by MTT assay
Cytotoxicity against mouse NIH3T3 cells after 72 hrs by MTT assay
[PMID: 18752941]
PA-1 IC50
3 μg/mL
Compound: 38
Cytotoxicity against human PA-1 cells after 72 hrs by MTT assay
Cytotoxicity against human PA-1 cells after 72 hrs by MTT assay
[PMID: 18752941]
SW-620 IC50
8.7 μg/mL
Compound: 38
Cytotoxicity against human SW620 cells after 72 hrs by MTT assay
Cytotoxicity against human SW620 cells after 72 hrs by MTT assay
[PMID: 18752941]
Molecular Weight

584.83

Formula

C38H52N2O3
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

OC(CNC([C@]12[C@@]([C@@H](CC2)C(C)=C)([H])[C@]3([H])[C@@](CC1)([C@]4([C@]([C@@]5([C@@](C(C)(C6=C(C7=CC=CC=C7N6)C5)C)([H])CC4)C)([H])CC3)C)C)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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DRF-4015 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DRF-4015905838-14-4DRF4015DRF 4015Drug DerivativeDrug derivativebetulinic acidantitumorInhibitorinhibitorinhibit

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