country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-146338

Copy Link Print Information

RPR103611

RPR103611, the betulinic acid derivative, is a potent HIV-1 entry inhibitor with IC₅₀s of 80, 0.27, and 0.17 for CCR5-tropic virus YU2, CXCR4-tropic virus NL4-3 and dual tropic virus 89.6, respectively.

For research use only. We do not sell to patients.

CAS No.: 150840-75-8
Formula: C₄₆H₇₈N₂O₆
Molecular Weight:755.12

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

RPR103611 Chemical Structure

CAS No.: 150840-75-8

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All HIV Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
H9	EC₅₀	0.03 μM Compound: 12	Toxic concentration on HIV-1 mock infected H9 lymphocyte cells Toxic concentration on HIV-1 mock infected H9 lymphocyte cells	[PMID: 8676334]
H9	IC₅₀	2.7 μM Compound: 12	Inhibitory activity against HIV-1 replication in mock infected H9 cells Inhibitory activity against HIV-1 replication in mock infected H9 cells	[PMID: 8676334]
TZM	CC₅₀	17 μM Compound: 2; RPR103611	Cytotoxicity against human TZM-bl cells assessed as reduction in cell viability by CellTitre-Glo assay Cytotoxicity against human TZM-bl cells assessed as reduction in cell viability by CellTitre-Glo assay	[PMID: 35513221]

Chemical Information

CAS No. 150840-75-8
Molecular Weight 755.12
Formula C₄₆H₇₈N₂O₆
SMILES

[H][C@@]12CC[C@@]3([C@](CC[C@@]4([C@]5([C@@H](CC[C@@]5(CC[C@]43C)C(NCCCCCCCC(N[C@H]([C@H](CC(O)=O)O)CC(C)C)=O)=O)C(C)=C)[H])[H])([C@]1(CC[C@@H](C2(C)C)O)C)[H])C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Reon Takeuchi, et al. Design, synthesis, and bio-evaluation of novel triterpenoid derivatives as anti-HIV-1 compounds. Bioorg Med Chem Lett. 2022 Aug 1;69:128768. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote

Amount: USD 0.00

Biological Activity
- Description
Chemical Information
Purity & Documentation
References

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Product Name:
CAS No.:
Species:
Purity:
Quantity:

RPR103611

All HIV Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

RPR103611 Related Classifications

HY-146338 Related Classifications