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Danshensu sodium salt (Synonyms: Sodium Danshensu; (±)-DanShenSu sodium sal)

Cat. No.: HY-N0106 Purity: >98.0%
Handling Instructions

Danshensu (sodium salt) is odium salt of danshensu from the widely used Chinese herb Danshen.

For research use only. We do not sell to patients.

Danshensu sodium salt Chemical Structure

Danshensu sodium salt Chemical Structure

CAS No. : 67920-52-9

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Danshensu (sodium salt) is odium salt of danshensu from the widely used Chinese herb Danshen. It can inhibited phenylephrine- and CaCl2-induced vasoconstriction in Ca2+-free medium. In vitro: Sodium danshensu showed a biphasic effects on vessel tension. While low dosage of sodium danshensu produced small contraction possibly through transient enhancement of Ca2+ influx, high dosage produced significant vasodilation mainly through promoting the opening of non-selective K+ channels and small-conductance calcium-sensitive K+ channels in the vascular smooth muscle cells.[1]In vivo: Danshensu did not change the expression of AGEs but partly blocked the increased expression of RAGE in the hippocampus of diabetic mice. Danshensu could ameliorate the cognitive decline in streptozotocin-induced diabetic mice by attenuating advanced glycation end product-mediated neuroinflammation.[2]

Molecular Weight

220.15

Formula

C₉H₉NaO₅

CAS No.

67920-52-9

SMILES

OC1=C(O)C=CC(CC(C([O-])=O)O)=C1.[Na+]

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 33 mg/mL (149.90 mM)

*"≥" means soluble, but saturation unknown.

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Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.5424 mL 22.7118 mL 45.4236 mL
5 mM 0.9085 mL 4.5424 mL 9.0847 mL
10 mM 0.4542 mL 2.2712 mL 4.5424 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Product Name:
Danshensu sodium salt
Cat. No.:
HY-N0106
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