1. Apoptosis
  2. TNF-alpha

Mesaconitine 

Cat. No.: HY-N0724 Purity: 99.55%
Data Sheet SDS Handling Instructions

Mesaconitine is the main active component of genus aconitum plants.

For research use only. We do not sell to patients.
Mesaconitine Chemical Structure

Mesaconitine Chemical Structure

CAS No. : 2752-64-9

Size Price Stock Quantity
10 mM * 1 mL in DMSO $139 In-stock
5 mg $100 In-stock
10 mg $150 In-stock
50 mg   Get quote  
100 mg   Get quote  

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  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Mesaconitine is the main active component of genus aconitum plants. IC50 value: Target: in vitro: In HUVECs, 30 microM mesaconitine increased the [Ca(2+)](i) level in the presence of extracellular CaCl(2) and NaCl, and the response was inhibited by KBR7943. Mesaconitine increased intracellular Na(+) concentration level in HUVECs. The [Ca(2+)](i) response by mesaconitine was inhibited by 100 microM D-tubocurarine [1]. Mesaconitine at 30 microM inhibited 3 microM phenylephrine-induced contraction in the endothelium-intact, but not endothelium-denuded, aortic rings [2]. MA promoted the alpha-MT-induced decrease in NE levels in hippocampus, medulla oblongata plus pons and spinal cord [3].

References
Molecular Weight

631.71

Formula

C₃₃H₄₅NO₁₁

CAS No.

2752-64-9

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Mesaconitine
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HY-N0724
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