1. Apoptosis
  2. TNF Receptor

Mesaconitine 

Cat. No.: HY-N0724 Purity: 99.55%
Handling Instructions

Mesaconitine is the main active component of genus aconitum plants.

For research use only. We do not sell to patients.

Mesaconitine Chemical Structure

Mesaconitine Chemical Structure

CAS No. : 2752-64-9

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 167 In-stock
Stock in the United States
Estimated Time of Arrival: December 31
5 mg USD 120 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
10 mg USD 180 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Mesaconitine is the main active component of genus aconitum plants. IC50 value: Target: in vitro: In HUVECs, 30 microM mesaconitine increased the [Ca(2+)](i) level in the presence of extracellular CaCl(2) and NaCl, and the response was inhibited by KBR7943. Mesaconitine increased intracellular Na(+) concentration level in HUVECs. The [Ca(2+)](i) response by mesaconitine was inhibited by 100 microM D-tubocurarine [1]. Mesaconitine at 30 microM inhibited 3 microM phenylephrine-induced contraction in the endothelium-intact, but not endothelium-denuded, aortic rings [2]. MA promoted the alpha-MT-induced decrease in NE levels in hippocampus, medulla oblongata plus pons and spinal cord [3].

References
Molecular Weight

631.71

Formula

C₃₃H₄₅NO₁₁

CAS No.

2752-64-9

SMILES

CO[[email protected]@H]1C2([[email protected]@](C[[email protected]@]3(O)[[email protected]@H]4OC(C5=CC=CC=C5)=O)([H])[[email protected]@]4([H])[[email protected]](OC(C)=O)([[email protected]@H](O)[[email protected]@H]3OC)C6C2N(C)C7)[[email protected]@]([[email protected]]6OC)([H])[[email protected]@]7(COC)[[email protected]](O)C1

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
Mesaconitine
Cat. No.:
HY-N0724
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