Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4595)
Related Products (4595)
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3-Fluoro-4-methoxybenzaldehyde
0 ImagesSynonyms: 3-Fluoro-para-anisaldehyde3-Fluoro-4-methoxybenzaldehyde (3-Fluoro-para-anisaldehyde) is a drug intermediate that can be used to synthesize the fluorinated derivative of Combretastatin A-4 (HY-N2146), which has anti-cancer activity.
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Sedoheptulose
0 ImagesSedoheptulose is a heptulose. Sedoheptulose, in the form of phosphate esters, functions as a metabolic intermediate in the pentose phosphate pathway. Sedoheptulose serves as a starting material for the chemical synthesis of pseudoaminosugars and chiral substituted furans.
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DL-3-Indolylglycine
0 ImagesDL-3-Indolylglycine is a compound intermediate and Amino acid derivative. DL-3-Indolylglycine can be used for the synthesis of serine protease inhibitors. DL-3-Indolylglycine is applicable to the research of thrombotic diseases.
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Demethyl-sapanisertib-C2-amide-PEG7-C2-N3
0 ImagesDemethyl-sapanisertib-C2-amide-PEG7-C2-N3 (Compound 10c) is an azide group linker used for coupling, which can be employed in the synthesis of "Rapa-Link" compounds, such as M-1111 (HY-176948), an mTOR inhibitor.
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L-Xylose-5-13C
0 ImagesSynonyms: L-(-)-Xylose-5-13C
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2-Chloro-3-pyridinol
0 Images2-Chloro-3-pyridinol is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 2-Chloro-3-pyridinol can also be used in the synthesis of other active compounds. In addition, 2-Chloro-3-pyridinol is a halopyridinol disinfection by-product in drinking water samples.
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(2-Dodecen-1-yl)succinic anhydride
0 ImagesCat. No.: HY-W009400CAS No.: 19780-11-1(2-Dodecen-1-yl)succinic anhydride is an organic compound commonly used in certain polymerization reactions. It is used in the manufacture of products such as plastics and resins, and is widely used in certain industrial fields, such as coatings, inks and textile manufacturing. In addition, the compound is also used as a raw material for pharmaceutical intermediates and surfactants.
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Olmesartan lactone impurity
0 ImagesOlmesartan lactone impurity is an impurity of Olmesartan (HY-17004). Olmesartan is an angiotensin II receptor (AT1R) antagonist that is used in hypertension research.
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2,5-Dibromo-4-methylpyridine
0 Images2,5-Dibromo-4-methylpyridine is a synthetic pyridine derivative and serves as an important intermediate.
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L-2-Aminobutyric acid-d6
0 ImagesSynonyms: H-Abu-OH-d6L-2-Aminobutyric acid-d6 is the deuterium labeled L-2-Aminobutyric acid. L-2-Aminobutyric acid is a non-proteinogenic amino acid that exists in human tissues and body fluids. L-2-Aminobutyric acid is formed by the transamination of oxobutyric acid. L-2-Aminobutyric acid can serve as a precursor for anticonvulsant and anti-tuberculosis agents and is a key intermediate in the chemical and pharmaceutical industries.
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Sodium Picosulfate
0 ImagesSynonyms: Sodium PicosulphateSodium Picosulfate (Sodium Picosulphate) is a contact irritant laxative with oral activity. Sodium Picosulfate inhibits the absorption of water and electrolytes, increasing their production. Sodium Picosulfate can be used in colonoscopy applications.
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Cbz-Valaciclovir
0 ImagesSynonyms: Benzyloxycarbonyl valacyclovir
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2-Chloro-4-nitropyridine
0 Images2-Chloro-4-nitropyridine is a drug intermediate in synthesizing other organic compounds, such as 2-chloro-4-ethoxypyridine and various RET kinase inhibitors.
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MFZ 2-13
0 ImagesCat. No.: HY-W722043CAS No.: 146725-34-0Synonyms: O-456MFZ 2-13 (O-456) is an N-demethylated intermediate and N-nor-analogue of MFD 2-12. MFZ 2-13 inhibits dopamine uptake through the human dopamine receptor with an IC50 of 1.4 nM.
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Doxepin-d3 hydrochloride
0 ImagesDoxepin-d3 hydrochloride is the deuterated-labeled Doxepin Hydrochloride (HY-B0725). Doxepin Hydrochloride is an orally active, blood-brain barrier penetrant tricyclic antidepressant with multiple activities including hypnosis, sedation, analgesia and vasodilation. Doxepin Hydrochloride enhances the expression of PSD-95 and synapsin 1 via the PI3K/AKT/mTOR signaling pathway, and is metabolized to DesmethylDoxepin Hydrochloride in vivo. Doxepin Hydrochloride can be used in research related to various diseases such as depression, anxiety, obesity and atopic dermatitis.
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Bamaquimast
0 ImagesSynonyms: F 10126; L 0042Bamaquimast (F 10126) is an anti-asthmatic agent and mediator release inhibitor. Bamaquimast can be used in the research of chronic obstructive bronchopulmonary disease.
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Cyclo(Arg-Gly-Asp-D-Tyr-ε-azido-Nle)
0 ImagesSynonyms: Azido-c(RGDyK)Cyclo(Arg-Gly-Asp-D-Tyr-ε-azido-Nle) (Azido-c(RGDyK)) is a polypeptide composed of arginine, glycine, aspartic acid, and tyrosine that can be used for Synthesis of [18F]FPyKYNE-c(RGDyK).
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L-Xylose-2-13C
0 ImagesSynonyms: L-(-)-Xylose-2-13C
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Photocaged DAP TFA
0 ImagesSynonyms: pm-DAP TFAPhotocaged DAP (pm-DAP) TFA is a protected version of 2,3-Diaminopropionic acid (DAP) (HY-W013673). Photocaged DAP TFA can produce 2,3-Diaminopropionic acid after photodeprotection. Photocaged DAP TFA can be used as an intermediate to capture biosynthetic acylase.
