Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11050)
Related Products (11050)
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4-Epitetracycline-d6
0 ImagesCat. No.: HY-W701205CAS No.: 2373374-43-54-Epitetracycline-d6 is deuterated labeled 4-Epitetracycline hydrochloride (HY-136443) 4-Epitetracycline hydrochloride is an epimer of Tetracycline (HY-A0107). Tetracycline can undergo epimerization insolution to 4-Epitetracycline hydrochloride, which shows a much lower antibiotic activity.
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15:0 SM (d18:1/15:0)-d9
0 Images15:0 SM (d18:1/15:0)-d9 is deuterium labeled 15:0 SM (d18:1/15:0).
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Estrone sulfate-d4 TEA
0 ImagesCat. No.: HY-113293S1Estrone sulfate-d4 TEA is the deuterium labeled Estrone sulfate TEA. Estrone sulfate is an inactive endogenous estrogen that can be converted into Estrone (HY-B0234) and Estradiol (HY-B0141). Estrone sulfate is also a substrate of the OATP1B3 transporter. Estrone sulfate can be converted into Estrone and Estradiol in normal mammary parenchymal cells. Estrone sulfate stimulates the growth of nitrosomethylurea-induced mammary tumors in ovariectomized rats and the colony formation of dispersed nitrosomethylurea mammary cells, with conversion into Estrone and Estradiol occurring both in vivo and in vitro during this process. Estrone sulfate is applicable to breast cancer-related research.
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Hexanoylglycine-13C2,15N
0 ImagesCat. No.: HY-113150S2CAS No.: 2483829-92-9Hexanoylglycine-13C2,15N is the 13C- and 15N-labeled Hexanoylglycine (HY-113150). Hexanoylglycine is an endogenous metabolite present in Urine that can be used for the research of Ethylmalonic Encephalopathy.
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Butylated hydroxyanisole-d18
0 ImagesCat. No.: HY-W077436S1CAS No.: 1185162-50-8Synonyms: 2,6-Di-Tert-Butyl-4-Methoxyphenol-d18Butylated hydroxyanisole-d18 (2,6-Di-Tert-Butyl-4-Methoxyphenol-d18) is the deuterium labeled Butylated hydroxyanisole.
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Dyclonine-d9 hydrochloride
0 ImagesCat. No.: HY-B0364ASSynonyms: Dyclocaine-d9 hydrochlorideDyclonine-d9 hydrochloride (Dyclocaine-d9 hydrochloride) is the deuterated-labeled Dyclonine hydrochloride (HY-B0364A). Dyclonine hydrochloride (Dyclocaine hydrochloride) is an orally active, blood-brain barrier-permeable piperidine phenylacetone small molecule commonly used as a local anesthetic. Dyclonine hydrochloride acts as a highly selective allosteric antagonist of TRPV3; it also reversibly inhibits G9a, ALDH2 and ALDH3A1, non-competitively blocks AChE. Dyclonine hydrochloride activates the Nrf2/ARE pathway, relieves the epigenetic silencing of FXN, blocks Aβ42 aggregation, and promotes remyelination and reparative polarization of microglia. Dyclonine hydrochloride alleviates pruritus via TRPV3 inhibition; it is used in studies of neurodegenerative disease models based on its AChE inhibitory, antioxidant and remyelinating effects; it sensitizes drug-resistant tumors through ALDH inhibition, and combined use with protease inhibitors induces more tumor cell apoptosis; it inhibits Candida albicans in vitro. Dyclonine hydrochloride can be used for research on multiple diseases including neurodegenerative diseases, cancer and pruritic dermatitis.
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Emoxypine-d5
0 ImagesCat. No.: HY-W002620SCAS No.: 2732874-77-8Synonyms: 2-Ethyl-3-hydroxy-6-methylpyridine-d5Emoxypine-d5 is deuterium labeled Emoxypine.
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Acetylcholine-d13 bromide
0 ImagesCat. No.: HY-B0282AS2Purity: 98.55%Synonyms: ACh-d13 bromideAcetylcholine-d13 (bromide) is the deuterium labeled Acetylcholine bromide.
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Roflumilast-d3
0 ImagesCat. No.: HY-15455S2CAS No.: 1189992-00-4Synonyms: APTA-2217-d3; BYK 20869-d3; B9302-107-d3Roflumilast-d3 is deuterium labeled Roflumilast. Roflumilast is a selective PDE4 inhibitor with IC50s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDEA4, PDEB1, and PDEB2, respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells.
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Chlorimuron-ethyl-d5
0 ImagesCat. No.: HY-W725647Chlorimuron-ethyl-d5 is the deuterium labeled Chlorimuron-ethyl (HY-W040262). Chlorimuron-ethyl induces oxidative stress. Chlorimuron-ethyl is an important herbicide that has been widely used in soybean production.
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(9S,13R)-12-Oxo phytodienoic acid-d5
0 ImagesCat. No.: HY-118828ASCAS No.: 2692624-08-9Synonyms: (9S,13R)-12-OPDA-d5(9S,13R)-12-OPDA-d5 ((9S,13R)-12-OPDA-d5) is an isotopic label of (9S,13R)-12-oxyphytodienoic acid. (9S,13R)-12-Oxophytodienoic acid is an isomer of 12-oxoPDA (HY-118828). (9S,13R)-12-Oxo phytodienoic Acid is a lipoxygenase metabolite in green plant leaves.
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4-Methoxyestrone-13C6
0 ImagesCat. No.: HY-128790S1
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Apolipoprotein E3, U-15N
0 ImagesCat. No.: HY-176303SApolipoprotein E3, U-15N is the 15N-labeled Apolipoprotein E3.
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2-Decanone-d5-1
0 ImagesCat. No.: HY-W010203S1CAS No.: 55320-60-02-Decanone-d5-1 is the deuterium labeled 2-Decanone (HY-W010203). 2-Decanone is an antifungal agent. 2-Decanone inhibits pathogen mycelial growth, spore germination, and appressorium formation. 2-Decanone downregulates spore germination-related genes (MfBmp1) and penetration structure formation genes (MfPls1), inducing reactive oxygen species (ROS) accumulation to trigger mitochondrial damage and subsequent spore apoptosis. 2-Decanone is promising for research of postharvest disease control in fruits and vegetables.
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trans-Resveratrol-4'-O-D-Glucuronide-d4
0 ImagesCat. No.: HY-118634SCAS No.: 1420291-58-2Synonyms: R-4G-d4trans-Resveratrol-4'-O-D-Glucuronide-d4 (R-4G-d4) is deuterium labeled trans-Resveratrol-4'-O-D-Glucuronide.
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Pimavanserin-d4
0 ImagesCat. No.: HY-14557S1Synonyms: ACP-103-d4Pimavanserin-d4 (ACP-103-d4) is the deuterium labeled Pimavanserin (HY-14557). Pimavanserin is a selective, brain-penetrant, inverse agonist of the 5-HT2A receptor with pIC50 and pKd of 8.73 and 9.3, respectively.
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Hexane-1,6-diamine dihydrochloride-d12
0 ImagesCat. No.: HY-W015248SSynonyms: Hexamethylenediamine Dihydrochloride-d12Hexane-1,6-diamine dihydrochloride-d12 (Hexamethylenediamine Dihydrochloride-d12) is the deuterium labeled Hexane-1,6-diamine dihydrochloride (HY-W015248).
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25-Desacetyl Rifampicin-d3
0 ImagesCat. No.: HY-125587SCAS No.: 2714485-01-325-Desacetyl Rifampicin-d3 is the deuterium labeled 25-Desacetyl Rifampicin.
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Lansoprazole sulfone-d4
0 ImagesCat. No.: HY-W008614SCAS No.: 1184999-77-6Synonyms: AG-1813-d4Lansoprazole sulfone (AG-1813)-d4 is the deuterium labeled Lansoprazole sulfone (HY-W008614). Lansoprazole sulfone, Lansoprazole (HY-13662) metabolite, is a H+, K+-ATPase inhibitor. Lansoprazole sulfone has potential applications in duodenal ulcer, gastric ulcer, gastroesophageal reflux disease and Zolinger Ellison disease.
