2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
  4. Calmodulin
  5. Calmodulin Inhibitor

Calmodulin Inhibitor

Calmodulin Inhibitors (9):

Cat. No. Product Name Effect Purity
  • HY-N7503
    Psoralenoside
    		Inhibitor 99.84%
    Psoralenoside is a benzofuran glycoside from Psoralea corylifolia. Psoralenoside exhibits high binding affinities against histaminergic H1, calmodulin, and voltage-gated L-type calcium channels (E-value≥-6.5 Kcal/mol). Psoralenoside shows estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity.
  • HY-N12405
    Encecalinol
    		Inhibitor
    Encecalinol, extracted from aerial parts of Ageratina grandifolia, is a potent inhibitor of calmodulin inhibitor.
  • HY-N10772
    Albanin A
    		Inhibitor
    Albanin A, a flavonoid, suppresses glutamate release by decreasing Ca2+/calmodulin/adenylate Cyclase 1 (AC1) activation in synaptosomes and exerts neuroprotective effect in vivo. Albanin A has anti-inflflammatory activity.
  • HY-P2471
    Neurogranin (48-76), mouse
    		Inhibitor
    Neurogranin (48-76), mouse is a peptide corresponding to residues 48-76 of Neurogranin. Neurogranin, a calmodulin-binding protein, is exclusively expressed in the post-synapse, and mediates NMDAR driven synaptic plasticity by regulating the calcium-calmodulin (Ca2+-CaM) pathway.
  • HY-100263
    Metofenazate
    		Inhibitor
    Metofenazate is a selective calmodulin inhibitor.
  • HY-N10198
    Acremonidin A
    		Inhibitor
    Acremonidin A is a potent calmodulin (CaM) inhibitor found in Purpureocillium lilacinum. Acremonidin A binds to the human calmodulin (hCaM) biosensor hCaM M124C-mBBr, with Kd of 19.40 nM.
  • HY-P1805
    Calmodulin Binding Peptide 1
    		Inhibitor
    Calmodulin Binding Peptide 1 is a high affinity (pM) CaM-binding peptide derived from smooth muscle myosin light-chain kinase (MLCK peptide), which strongly inhibits IP3-induced Ca2+ release .
  • HY-142087
    Beauverolide Ja
    		Inhibitor
    Beauverolide Ja, a cyclotetradepsipeptide, is a potent calmodulin (CaM) inhibitor with a Kd of 0.078 μM and a Ki of 0.39 μM for Ca2+-CaM. Beauverolide Ja is a secondary metabolite of Isaria fumosorosea.
  • HY-P1874
    Calmodulin-Dependent Protein Kinase II (281-309)
    		Inhibitor
    Calmodulin-Dependent Protein Kinase II (281-309) is a peptide of calcium/calmodulin-dependent protein kinase II (CaM-kinase II).