2561494-76-4
2561494-76-4
Chemical Structure
SGC-CAMKK2-1
- CAS No.: 2561494-76-4
- Formula:C26H23NO3
- Molecular Weight:397.47
InChIKey: TXIYVFVMXNFNRX-UHFFFAOYSA-N
SMILES: O=C(C1=C(C2CCCC2)C=C(C3=COC4=NC=C(C5=CC(C)=CC=C5)C=C43)C=C1)O
Biological Activity: SGC-CAMKK2-1, a chemical probe, is the selective, inhibitor for calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) with an IC50 of 30 nM. SGC-CAMKK2-1 inhibits AMPK phosphorylation in cell C4-2 with an IC50 of 1.6 μM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SGC-CAMKK2-1 | 98.8% | SGC-CAMKK2-1, a chemical probe, is the selective, inhibitor for calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) with an IC50 of 30 nM. SGC-CAMKK2-1 inhibits AMPK phosphorylation in cell C4-2 with an IC50 of 1.6 μM. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.69
HY-15192GSK 650394 -
Similarity Score 0.56
HY-162009CaMKK2-IN-1 -
Similarity Score 0.50
HY-162293CDK8-IN-14 -
Similarity Score 0.48
HY-144425BSc5367 -
Similarity Score 0.47
HY-110322APPTN -
Similarity Score 0.47
HY-110322PPTN hydrochloride -
Similarity Score 0.46
HY-181549PDE4-IN-32 -
Similarity Score 0.46
HY-105369KF-20444 -
Similarity Score 0.46
HY-176224Anti-virulence factor-IN-2 -
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