120634-86-8
Chemical Structure
KS 501
- CAS No.: 120634-86-8
- Formula:C33H48O10
- Molecular Weight:604.73
IUPAC Name: 3-heptyl-5-hydroxyphenyl 2-(((2R,3S,4R,5S)-5-((R)-1,2-dihydroxyethyl)-3,4-dihydroxytetrahydrofuran-2-yl)oxy)-6-heptyl-4-hydroxybenzoate
InChIKey: MPAXORHHSMKMHV-PPJKYQRASA-N
SMILES: CCCCCCCC1=CC(O)=CC(OC(C(C(CCCCCCC)=CC(O)=C2)=C2O[C@@H]3O[C@@]([C@@H]([C@H]3O)O)([H])[C@H](O)CO)=O)=C1
Biological Activity: KS 501 is a potent and selective calmodulin inhibitor. KS 501 inhibits the activation of calmodulin kinase I and II, but has less effect against cyclic adenosine 3’,5’-monophosphate (cyclic AMP)-sensitive kinase. KS 501 inhibits the enzyme through interfering with calmodulin activation rather than through a direct effect on the enzyme. KS 501 can be used for the study of leukemia[1].
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KS 501 | KS 501 is a potent and selective calmodulin inhibitor. KS 501 inhibits the activation of calmodulin kinase I and II, but has less effect against cyclic adenosine 3’,5’-monophosphate (cyclic AMP)-sensitive kinase. KS 501 inhibits the enzyme through interfering with calmodulin activation rather than through a direct effect on the enzyme. KS 501 can be used for the study of leukemia. | |||||||||||||||||||||
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