Beauverolide Ja
Beauverolide Ja, a cyclotetradepsipeptide, is a potent calmodulin (CaM) inhibitor with a Kd of 0.078 μM and a Ki of 0.39 μM for Ca2+-CaM. Beauverolide Ja is a secondary metabolite of Isaria fumosorosea.
For research use only. We do not sell to patients.
- CAS No.: 76265-41-3
- Formula: C35H46N4O5
- Molecular Weight:602.76
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
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Fungal Metabolite |
Chemical Information
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CAS No. 76265-41-3
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Molecular Weight 602.76
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Formula C35H46N4O5
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SMILES
O=C(N[C@H](C(N[C@](C(OC(CC(N1)=O)C(C)CCCC)=O)([H])[C@@H](C)CC)=O)CC2=CC=CC=C2)[C@@H]1CC3=CNC4=CC=CC=C34
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Structure Classification
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Initial Source
Beauveria sp.
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Abraham Madariaga-Mazón, et al. Potent anti-calmodulin activity of cyclotetradepsipeptides isolated from Isaria fumosorosea using a newly designed biosensor. Nat Prod Commun. 2015 Jan;10(1):113-6. [Content Brief]
[2]. Qunfang Weng, et al. Secondary Metabolites and the Risks of Isaria fumosorosea and Isaria farinose. Molecules. 2019 Feb 13;24(4):664. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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