Metofenazate
Based on 1 Customer Validation
Metofenazate is a selective calmodulin inhibitor.
For research use only. We do not sell to patients.
- Purity: 98.73%
- CAS No.: 388-51-2
- Formula: C31H36ClN3O5S
- Molecular Weight:598.15
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Membrane Transporter/Ion Channel Compound Library
HY-L011
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Autophagy Compound Library
HY-L029
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Highly Selective Inhibitors Library
HY-L158
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Cell Death Library
HY-L162
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Ion Channel Compound Library
HY-L166
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
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High-Throughput Bioactive Compound Library
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Biological Activity
Calmodulin[1]
Chemical Information
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CAS No. 388-51-2
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Appearance Oil
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Molecular Weight 598.15
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Formula C31H36ClN3O5S
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Color Colorless to light yellow
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SMILES
O=C(OCCN1CCN(CCCN2C3=C(C=CC=C3)SC4=CC=C(Cl)C=C24)CC1)C5=CC(OC)=C(OC)C(OC)=C5
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Synonyms
Methophenazine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (167.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6718 mL | 8.3591 mL | 16.7182 mL | 41.7955 mL |
| 5 mM | 0.3344 mL | 1.6718 mL | 3.3436 mL | 8.3591 mL | |
| 10 mM | 0.1672 mL | 0.8359 mL | 1.6718 mL | 4.1796 mL | |
| 15 mM | 0.1115 mL | 0.5573 mL | 1.1145 mL | 2.7864 mL | |
| 20 mM | 0.0836 mL | 0.4180 mL | 0.8359 mL | 2.0898 mL | |
| 25 mM | 0.0669 mL | 0.3344 mL | 0.6687 mL | 1.6718 mL | |
| 30 mM | 0.0557 mL | 0.2786 mL | 0.5573 mL | 1.3932 mL | |
| 40 mM | 0.0418 mL | 0.2090 mL | 0.4180 mL | 1.0449 mL | |
| 50 mM | 0.0334 mL | 0.1672 mL | 0.3344 mL | 0.8359 mL | |
| 60 mM | 0.0279 mL | 0.1393 mL | 0.2786 mL | 0.6966 mL | |
| 80 mM | 0.0209 mL | 0.1045 mL | 0.2090 mL | 0.5224 mL | |
| 100 mM | 0.0167 mL | 0.0836 mL | 0.1672 mL | 0.4180 mL |
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