Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4615)
Related Products (4615)
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2-Methylindanone
0 Images2-Methylindanone is a cyclic ketone compound. 2-Methylindanone is an important substrate for evaluating the effects of Pd and Ni in asymmetric α-arylation reactions. 2-Methylindanone can also be used as a drug intermediate.
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tert-Butyl 4-(2-carbamoylbenzofuran-5-yl)piperazine-1-carboxylate
0 Imagestert-Butyl 4-(2-carbamoylbenzofuran-5-yl)piperazine-1-carboxylate is a drug intermediate for synthesis of various active compounds.
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Dimethyl (3,3-difluoro-2-oxoheptyl)phosphonate
0 ImagesDimethyl (3,3-difluoro-2-oxoheptyl)phosphonate is a drug intermediate for synthesis of various active compounds.
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(2R,3S)-2-(4-(Cyclopentylamino)phenyl)-1-(2-fluoro-6-methylbenzoyl)piperidine-3-carboxylic acid
0 Images(2R,3S)-2-(4-(Cyclopentylamino)phenyl)-1-(2-fluoro-6-methylbenzoyl)piperidine-3-carboxylic acid is a drug intermediate for synthesis of various active compounds.
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4,5,6,7-Tetrahydrobenzo[d]isoxazol-5-amine hydrochloride
![4,5,6,7-Tetrahydrobenzo[d]isoxazol-5-amine hydrochloride](https://file.medchemexpress.com/product_pic/hy-w249042.gif "Click to View 4,5,6,7-Tetrahydrobenzo[d]isoxazol-5-amine hydrochloride Product Detail")
0 Images4,5,6,7-Tetrahydrobenzo[d]isoxazol-5-amine hydrochloride is a drug intermediate for synthesis of various active compounds.
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2-Amino-6-bromopyridine
0 Images2-Amino-6-bromopyridine is an intermediate. 2-Amino-6-bromopyridine is also a PqsR ligand with a Kd value of 6.8 μM in SPR assay. 2-Amino-6-bromopyridine shows weak antagonistic activity. 2-Amino-6-bromopyridine can be used in the synthesis of JAK2 inhibitors, MSK1 inhibitors, and in the research of Pseudomonas aeruginosa infection.
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Methyl 1-(2-chloroacetyl)-2-oxoindoline-6-carboxylate
0 ImagesCat. No.: HY-I1232CAS No.: 1160293-25-3Synonyms: Nintedanib-018Methyl 1-(2-chloroacetyl)-2-oxoindoline-6-carboxylate (Nintedanib-018) is a drug intermediate for synthesis of various active compounds.
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6-Aminonicotinic acid
0 Images6-Aminonicotinic acid is an analog of Niacin (HY-B0143) and also a GABAA receptor agonist with a Ki value of 4.4 μM in rats. 6-Aminonicotinic acid binds to both native and recombinant GABAA receptors, is metabolized into non-functional pyridine nucleotide analogs to inhibit dehydrogenases, and suppresses the proliferation of T2 bacteriophages. 6-Aminonicotinic acid accumulates in specific bacterial cells in the form of pyridine nucleotide analog metabolites. 6-Aminonicotinic acid can be used in research related to neurological disorders such as anxiety, epilepsy and schizophrenia, and also serves as an intermediate in organic synthesis.
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Potassium tert-butyl malonate
0 ImagesCat. No.: HY-42904CAS No.: 75486-33-8Potassium tert-butyl malonate is an intermediate in the synthesis of malonate monoester potassium salt.
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5-Ethoxypyrrolidin-2-one
0 Images5-Ethoxypyrrolidin-2-one is a drug intermediate for synthesis of various active compounds.
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(S)-Methyl 2-(6-hydroxy-2,3-dihydrobenzofuran-3-yl)acetate
0 Images(S)-Methyl 2-(6-hydroxy-2,3-dihydrobenzofuran-3-yl)acetate is a drug intermediate for synthesis of various active compounds.
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1-Brom-4,5-dimethyl-2-nitro-benzol
0 Images1-Brom-4,5-dimethyl-2-nitro-benzol is a drug intermediate for synthesis of various active compounds.
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(R)-tert-Butyl 4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
0 Images(R)-tert-Butyl 4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate is a drug intermediate for synthesis of various active compounds.
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2,3-Pentanedione
0 Images2,3-Pentanedione is a common constituent of synthetic flavorings and is used to impart a butter, strawberry, caramel, fruit, rum, or cheese flavor in beverages, ice cream, candy, baked goods, gelatins, and puddings. 2,3-Pentanedione also occurs naturally as a fermentation product in beer, wine, and yogurt and is releasedduring roasting of coffee beans.
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5-((S)-2,2-Dimethyltetrahydro-2H-pyran-4-yl)-1-((1S,2S)-2-methyl-1-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)cyclopropyl)-1H-indole-2-carboxylic acid
0 Images5-((S)-2,2-Dimethyltetrahydro-2H-pyran-4-yl)-1-((1S,2S)-2-methyl-1-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)cyclopropyl)-1H-indole-2-carboxylic acid (Compound 31k) is an intermediate of Orforglipron (HY-11218).
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4-Methyl-2,3-dihydrocyclopenta[b]indol-1(4H)-one
![4-Methyl-2,3-dihydrocyclopenta[b]indol-1(4H)-one](https://file.medchemexpress.com/product_pic/hy-75357.gif "Click to View 4-Methyl-2,3-dihydrocyclopenta[b]indol-1(4H)-one Product Detail")
0 ImagesSynonyms: 4-Methyl-3,4-dihydro-2h-cyclopenta[b]indol-1-one4-Methyl-2,3-dihydrocyclopenta[b]indol-1(4H)-one (4-Methyl-3,4-dihydro-2h-cyclopenta[b]indol-1-one) is a drug intermediate for synthesis of various active compounds.
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Benzo[h]quinoline
![Benzo[h]quinoline](https://file.medchemexpress.com/product_pic/hy-w004769.gif "Click to View Benzo[h]quinoline Product Detail")
0 ImagesSynonyms: α-NaphthoquinolineBenzo[h]quinolone is a widespread environmental pollutant. Benzo[h]quinolone is mutagenic. Benzo(h)quinoline derivatives can serve as G-quadruplex binding agents.
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3-(Prop-2-yn-1-yloxy)aniline hydrochloride
0 Images3-(Prop-2-yn-1-yloxy)aniline hydrochloride is a drug intermediate for synthesis of various active compounds.
