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Drug Intermediate

Drug Iintermediate

Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].

Drug Intermediate Related Products (4377):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-168940B
    NH2-PEG2000-COOH
    		99.87%
    NH2-PEG2000-COOH is a heterofunctional polyethylene glycol with one amino terminal group and one carboxyl terminal group. NH2-PEG2000-COOH reacts with N-succinimidyl-6-maleimidohexanoate to introduce a maleimide terminal group, followed by conjugation with thiolated RGD peptide via a thiol-maleimide coupling reaction to synthesize RGD-PEG-COOH. NH2-PEG2000-COOH can be used in cancer research.
    NH2-PEG2000-COOH
  • HY-W015800
    L-Homoserine lactone hydrochloride
    		99.88%
    L-Homoserine lactone hydrochloride is the core structural unit of the bacterial quorum-sensing signal molecule N-acyl-L-homoserine lactone (AHLs). As an important intermediate, L-Homoserine lactone hydrochloride acylated derivatives have potent immunosuppressive activity.
    L-Homoserine lactone hydrochloride
  • HY-W016644
    (S)-1-Benzylpyrrolidin-3-ol
    		99.90%
    (S)-1-Benzylpyrrolidin-3-ol (Compound 14) can be used to synthesis impurities of the anti-hypertensive agent Barnidipine hydrochloride (HY-107322).
    (S)-1-Benzylpyrrolidin-3-ol
  • HY-34611
    Boc-L-2,4-Diaminobutyric acid
    		98.0%
    Boc-L-2,4-Diaminobutyric acid (N-Boc-L-2,4-diaminobutyric acid; Boc-Dab-OH) is a versatile synthetic starting material with a cleavable protecting group. Boc-L-2,4-Diaminobutyric acid not only reduces the backbone cleavage rate by protecting the side-chain γ-amino group, but also triggers intramolecular cyclization of self-immolative linkers under acidic cleavage conditions, thus constructing stimuli-responsive materials. Boc-L-2,4-Diaminobutyric acid is also an important building block for bioactive molecules. It can be used in the synthesis of ASCT2 (SLC1A5) inhibitors and carboxynorspermine, and can also serve as an internal standard to support the quantitative detection of specific intracellular amino acids by UPLC-QQQ-MS.
    Boc-L-2,4-Diaminobutyric acid
  • HY-W157376
    PAMAM Dendrimer G0.0 amine (20% in methanol)
    PAMAM Dendrimer G0.0 amine is a pore-forming channel antagonist, including anthrax toxin protective antigen 63 (PA63, IC50 = 231 nM) and C. botulinum C2 toxin subunit (C2IIa, IC50 = 940 nM). At concentrations of 10 and 20 µM, PAMAM Dendrimer G0.0 amine reduces C2 toxin-induced death in HeLa cells. Additionally, PAMAM Dendrimer G0.0 amine is a chelator of nickel. In complexes with polysulfone membrane-bound chitosan, PAMAM Dendrimer G0.0 amine selectively captures and stores carbon dioxide (CO2) in a gas-feed system. PAMAM Dendrimer G0.0 amine has been used in the synthesis of PAMAM Dendrimer G0.5 Carboxylate (CAS 339334-01-9) and PAMAM Dendrimer G1.0 Amine (CAS 142986-44-5). PAMAM Dendrimer G0.0 amine can be used in research related to infections, cancer, and drug delivery systems.
    PAMAM Dendrimer G0.0 amine (20% in methanol)
  • HY-W001851
    1-Benzylpyrrole-2,5-dione
    		99.88%
    1-Benzylpyrrole-2,5-dione (N-Benzylmaleimide) is a heterocyclic compound containing a maleimide ring and a benzyl group. 1-Benzylpyrrole-2,5-dione can be used as a key reactant for the green chemical modification of cellulose nanocrystals (CNC).
    1-Benzylpyrrole-2,5-dione
  • HY-W021597
    N-Boc-5-bromoindole
    		99.98%
    N-Boc-5-bromoindole is formed as an intermediate for the synthesis of di-Boc-protected 5-aminoindole via a Buchwald-Hartwig amination with tBu-carbamate followed by regioselective bromination.
    N-Boc-5-bromoindole
  • HY-Y0084
    3,4,5-Trimethoxybenzoic acid
    		99.90%
    3,4,5-Trimethoxybenzoic acid (Eudesmic acid;Trimethylgallic Acid) is a benzoic acid derivative. A building block in medicine and organic synthesis. 3,4,5-Trimethoxybenzoic acid exhibits antibacterial activity against S. aureus with MIC of 0.97 μg/mL.
    3,4,5-Trimethoxybenzoic acid
  • HY-78197
    3,5-Dimethylisoxazole-4-boronic acid pinacol ester
    		99.07%
    3,5-Dimethylisoxazole-4-boronic acid pinacol ester is a drug intermediate that can be used for the synthesis of bromodomain inhibitors.
    3,5-Dimethylisoxazole-4-boronic acid pinacol ester
  • HY-W016656
    4-Phenylurazole
    		99.73%
    4-Phenylurazole (4-Phenyl-1,2,4-triazolidine-3,5-dione) is an important intermediate. 4-Phenylurazole also serves as a photographic emulsion stabilizer and a lubricant additive.
    4-Phenylurazole
  • HY-W007367
    2,6-Dichloropurine
    		99.81%
    2,6-Dichloropurine is a pharmaceutical intermediate. 2,6-Dichloropurine can be used to synthesize various PDE inhibitors, human A3 adenosine receptor (AR) antagonists, and CDK inhibitors.
    2,6-Dichloropurine
  • HY-32954
    2-Chloropyridine-4-boronic acid
    		99.95%
    2-Chloropyridine-4-boronic acid is an intermediate. 2-Chloropyridine-4-boronic acid can be used in the synthesis of nAChR agonists. 2-Chloropyridine-4-boronic acid can be used in cancer research.
    2-Chloropyridine-4-boronic acid
  • HY-20362
    4-Azaindole
    		99.57%
    4-Azaindole is a scaffold. 4-Azaindole can be used in the synthesis of Nav1.2 inhibitors. 4-Azaindole can be used in epilepsy and breast cancer research.
    4-Azaindole
  • HY-W046071
    N-Boc-trans-4-fluoro-L-proline
    		98.0%
    N-Boc-trans-4-fluoro-L-proline is a non-natural amino acid substitute used to construct monoclonal antibodies that specifically target the seed conformation of tau protein.
    N-Boc-trans-4-fluoro-L-proline
  • HY-131124
    7-Amino-3-chloro cephalosporanic acid
    		99.35%
    7-Amino-3-chloro cephalosporanic acid (7-ACCA) is an important intermediate for the synthesis of the second generation cephalosporins Cefaclor (HY-B0198).
    7-Amino-3-chloro cephalosporanic acid
  • HY-158243
    Fallypride precursor
    		98.92%
    Fallypride precursor (Compound 15) is a drug intermediate that can be used for synthesis of Fallypride (HY-135497).
    Fallypride precursor
  • HY-Y0421
    Adamantanone
    		≥98.0%
    Adamantane is a compound used in the synthesis of N-Boc-1,2,4-trioxane.
    Adamantanone
  • HY-W002314
    2-Bromo-4'-hydroxyacetophenone
    		98.57%
    2-Bromo-4'-hydroxyacetophenone is a PTP1B inhibitor with a Ki value of 42 μM. 2-Bromo-4'-hydroxyacetophenone is also an intermediate. 2-Bromo-4'-hydroxyacetophenone can be used in the synthesis of LXRα/β antagonists. 2-Bromo-4'-hydroxyacetophenone can be used in research on hematological diseases.
    2-Bromo-4'-hydroxyacetophenone
  • HY-49412
    Fmoc-Gly-Gly-Phe-Gly-NH-CH2-O-CO-CH3
    		98.68%
    Fmoc-Gly-Gly-Phe-Gly-NH-CH2-O-CO-CH3 (compound DC-13-C) is an intermediate in the synthesis of Exatecan (HY-13631) derivatives.
    Fmoc-Gly-Gly-Phe-Gly-NH-CH2-O-CO-CH3
  • HY-66052
    3-Amino-5-bromopyridine
    		99.95%
    3-Amino-5-bromopyridine is an intermediate and antibacterial agent. 3-Amino-5-bromopyridine inhibits the growth of S. aureus and E. coli. 3-Amino-5-bromopyridine can be used in K-ABP synthesis.
    3-Amino-5-bromopyridine