2. Signaling Pathways
  3. GPCR/G Protein
  4. PTHR
  5. PTHR Agonist

PTHR Agonist

PTHR Isoform Comparison

PTHR Agonists (11):

Cat. No. Product Name Effect Purity
  • HY-P0059
    Teriparatide
    		Agonist 99.98%
    Teriparatide (Human parathyroid hormone-(1-34)) is a PTH1 receptor agonist. Teriparatide (Human parathyroid hormone-(1-34)) can be used for osteoporosis research.
  • HY-100856
    PCO371
    		Agonist 99.67%
    PCO371 is an orally active full agonist of parathyroid hormone receptor 1 (PTHR1), with no effect on PTH type 2 receptor.
  • HY-176945
    PTH1R agonist 3
    		Agonist
    PTH1R agonist 3 (Example 47) is a parathyroid hormone 1 receptor (PTH1R) agonist with a pEC50 value of less than 6. PTH1R agonist 3 can be used for the study of bone diseases, such as osteoporosis.
  • HY-176944
    PTH1R agonist 2
    		Agonist
    PTH1R agonist 2 (example 3) is a parathyroid hormone 1 receptor (PTH1R) agonist. PTH1R agonist 2 can be used for research of hypoparathyroidism and osteoporosis.
  • HY-P1852
    TIP 39, Tuberoinfundibular Neuropeptide
    		Agonist 99.84%
    TIP 39, Tuberoinfundibular Neuropeptide is an endogenous PTH2 receptor agonist and antihypertensive agent. TIP 39, Tuberoinfundibular Neuropeptide selectively activates the PTH2 receptor with no activity on the PTH1 receptor, stimulates cAMP production, activates adenylate cyclase, and elevates intracellular calcium levels via mobilization from intracellular stores. TIP 39, Tuberoinfundibular Neuropeptide is highly conserved in humans, mice, and rats. TIP 39, Tuberoinfundibular Neuropeptide is applicable to research related to nociception and inflammation-induced pain.
  • HY-15103
    AH3960
    		Agonist 99.92%
    AH3960 (compound 16c) is an antagonist of androgen receptor. AH3960 binds wild as well as T877 mutant type androgen receptors. AH3960 selectively inhibits T877 with an IC50 value of 0.82 μM. AH3960 also serves as an agonist of parathyroid hormone receptor-1 (PTHR1).
  • HY-P0059A
    Teriparatide acetate hydrate
    		Agonist
    Teriparatide acetate hydrate (Human parathyroid hormone-(1-34) acetate hydrate) is a PTH1 receptor agonist. Teriparatide acetate hydrate (Human parathyroid hormone-(1-34) acetate hydrate) can be used for osteoporosis research.
  • HY-176943
    PTH1R agonist 1
    		Agonist
    PTH1R agonist 1 (Example 2) is a parathyroid hormone 1 receptor (PTH1R) agonist. PTH1R agonist 1 can be used for research of hypoparathyroidism and osteoporosis.
  • HY-120398
    CH5447240
    		Agonist
    CH5447240 is an agonist for parathyroid hormone receptor 1 (PTHR1), that inhibits human PTHR1 with an EC50 of 12 μM. CH5447240 exhibits good metabolic stability in human liver microsomes. CH5447240 increases serum calcium levels in rats. CH5447240 can be used in research about hypoparathyroidism.
  • HY-100856R
    PCO371 (Standard)
    		Agonist
    PCO371 (Standard) is the analytical standard of PCO371 (HY-100856). This product is intended for research and analytical applications. PCO371 is an orally active full agonist of parathyroid hormone receptor 1 (PTHR1), with no effect on PTH type 2 receptor.
  • HY-176946
    PTH1R agonist 4
    		Agonist
    PTH1R agonist 4 (Example 63) is a parathyroid hormone 1 receptor (PTH1R) agonist with a pEC50 value greater than 7. PTH1R agonist 4 can be used for the study of bone diseases, such as osteoporosis.