PTH1R agonist 3
PTH1R agonist 3 (Example 47) is a parathyroid hormone 1 receptor (PTH1R) agonist with a pEC50 value of less than 6. PTH1R agonist 3 can be used for the study of bone diseases, such as osteoporosis.
For research use only. We do not sell to patients.
- CAS No.: 3106619-38-6
- Formula: C24H36N6O6
- Molecular Weight:504.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
PTH1R < 6 (pEC50) |
Chemical Information
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CAS No. 3106619-38-6
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Molecular Weight 504.58
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Formula C24H36N6O6
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SMILES
N/C(N)=C(C1=O)\C(N(C(N1[C@@H]2CC[C@](C)(CC2)CN3C4(C(NC3=O)=O)CCOCC4)=O)CCCC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Endocrine Diseases
Endocrine diseases often arise from disrupted hormone production, hormone signaling, or target-tissue responsiveness; for diabetes-focused endocrine disease models, insulin signaling regulates glucose uptake, hepatic glucose output, lipid metabolism, and β-cell compensation. Type 2 diabetes develops through interacting defects in insulin resistance, β-cell dysfunction, adipose inflammation, hepatic glucose overproduction, altered incretin signaling, and ectopic lipid metabolism. A major unresolved question is whether endocrine dysfunction is driven primarily by target-tissue insulin resistance, intrinsic β-cell failure, immune/inflammatory stress, or combined multi-organ failure that differs by disease stage.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PTH1R agonist 3 Related Classifications
HY-176945 Related Classifications
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