Clec4d - C-type lectin domain family 4, member d Gene

Also Known as mcl; Mpcl; Clecsf8

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17474

Summary

Enables immunoglobulin receptor binding activity. Involved in Antifungal innate immune response; positive regulation of I-kappaB kinase/NF-kappaB signaling; and positive regulation of myeloid dendritic cell activation. Acts upstream of or within several processes, including Fc-gamma Receptor signaling pathway; T cell differentiation involved in immune response; and defense response to Other organism. Located in plasma membrane. Is expressed in bone marrow; lung; lymph node; and spleen. Orthologous to human CLEC4D (C-type lectin domain family 4 member D). [provided by Alliance of Genome Resources, Apr 2022]

Clec4d Products (2)

mRNA Protein Name
NM_001163161.1 NP_001156633.1 C-type lectin domain family 4 member D isoform 2
NM_010819.4 NP_034949.3 C-type lectin domain family 4 member D isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables immunoglobulin receptor binding IPI
IPI: Inferred from physical interaction
23602766 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within Fc-gamma receptor signaling pathway IDA
IDA: Inferred from direct assay
23602766 MGI
acts upstream of or within T cell differentiation involved in immune response IMP
IMP: Inferred from mutant phenotype
23602766 MGI
acts upstream of or within adaptive immune response IMP
IMP: Inferred from mutant phenotype
23602766 MGI
involved in antifungal innate immune response IMP
IMP: Inferred from mutant phenotype
23911656 MGI
acts upstream of or within defense response to bacterium IMP
IMP: Inferred from mutant phenotype
23602766 MGI
acts upstream of or within innate immune response IMP
IMP: Inferred from mutant phenotype
23602766 MGI
involved in positive regulation of canonical NF-kappaB signal transduction IMP
IMP: Inferred from mutant phenotype
23911656 MGI
involved in positive regulation of myeloid dendritic cell activation IMP
IMP: Inferred from mutant phenotype
23602766 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in plasma membrane IDA
IDA: Inferred from direct assay
23602766 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

C-type lectin domain family 4 member D

  • C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 8

  • C-type lectin, superfamily member 8

  • DC-associated C-type lectin 3

  • dectin-3

  • dendritic cell-associated C-type lectin 3

  • macrophage C-type lectin

  • macrophage-restric

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS02793 CLEC4D Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19771 Clec4d Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26268 Clec4d Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Clec4d NCBI NCBI:338339