1 Result for "

Y-320

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Y-320" in MCE Product Catalog:

7
7 Cited Publications
Art. -Nr.: HY-15898
CAS. Nr.: 288250-47-5
Reinheit:  99.03%
Forschungsgebiete:  

Inflammation/Immunology Cancer

Y-320 is a potent, orally active phenylpyrazoleanilide immunomodulator. Y-320 inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 values of 20 to 60 nM. Y-320 enhances TP53, DMD, and COL17A1 PTC readthrough by G418 and increases cellular protein levels and protein synthesis. Y-320 concomitants use of with a low dose of Paclitaxel (HY-B0015) significantly sensitized multidrug resistance (MDR) tumors by inducing G2/M phase arrest and apoptosis. Y-320 can be used for research of rheumatoid arthritis (RA) and cancer .
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