Kallikrein-11

Definition:

Possible multifunctional protease. Efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin. Cleaves synthetic peptides after arginine but not lysine residues.

References:

[1]. S Mitsui, et al. A novel isoform of a kallikrein-like protease, TLSP/hippostasin, (PRSS20), is expressed in the human brain and prostate. Biochem Biophys Res Commun. 2000 May 27;272(1):205-11. [Content Brief]

[2]. Liu-Ying Luo, et al. Purification and characterization of human kallikrein 11, a candidate prostate and ovarian cancer biomarker, from seminal plasma. Clin Cancer Res. 2006 Feb 1;12(3 Pt 1):742-50. [Content Brief]

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