Cat. No.: HY-W134163

(E)-2-Octenal

(Synonyms: trans-2-Octenal)

Customer Review

Based on 1 Customer Validation

(E)-2-Octenal is an Antifungal agent. (E)-2-Octenal disrupts cell membrane integrity and causes ROS accumulation. (E)-2-Octenal decreases the activities of phosphofructokinase and pyruvate kinase. (E)-2-Octenal inhibits Neofusicoccum parvum growth by disrupting mitochondrial energy metabolism. (E)-2-Octenal suppresses the growth of a Prochloraz (HY-B0845)-resistant Penicillium italicum strain. (E)-2-octenal exerts a broad-spectrum and potent inhibitory effect on various fungi, including Sclerotium rolfsii, Metarhizium anisopliae sensu lato, and Aspergillus flavus, etc. (E)-2-Octenal can be used for the research of citrus blue mold and mango stem-end rot.

For research use only. We do not sell to patients.

Purity: 99.29%
CAS No.: 2548-87-0
Formula: C₈H₁₄O
Molecular Weight:126.20

Storage:

-20°C, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

(E)-2-Octenal Chemical Structure

CAS No.: 2548-87-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Solvent & Solubility
- In Vitro
- In Vivo
Purity & Documentation
References
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

(E)-2-octenal (0.25-2.00 mL L⁻¹; 2-4 d) inhibits the mycelial growth of prochloraz-resistant Penicillium italicum strain XX5 with an MIC of 0.25 mL L⁻¹ and MFC of 0.50 mL L⁻¹^[1].
(E)-2-octenal (1/2 MIC-MIC; 30-120 min) induces dose- and time-dependent oxidative stress in prochloraz-resistant Penicillium italicum strain XX5 mycelia, leading to ROS accumulation and lipid peroxidation^[1].
(E)-2-octenal (0.1-1.6 μL/mL; 1-4 days) inhibits mycelial growth of Neofusicoccum parvum in a concentration-dependent manner, with minimum inhibitory concentration (MIC) 0.4 μL/mL and minimum fungicidal concentration (MFC) 0.8 μL/mL^[2].
(E)-2-octenal (0.2-0.4 μL/mL) damages the morphology of Neofusicoccum parvum mycelia, with more severe damage at higher concentrations^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2548-87-0
Appearance Liquid (Density: 0.846 g/cm³)
Molecular Weight 126.20
Formula C₈H₁₄O
SMILES

CCCCC/C=C/C=O
Synonyms

trans-2-Octenal
Structure Classification
- Others
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : ≥ 200 mg/mL (1584.79 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

* "≥" means soluble, but saturation unknown.

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

7.9239 mL

39.6197 mL

79.2393 mL

5 mM

1.5848 mL

7.9239 mL

15.8479 mL

10 mM

0.7924 mL

3.9620 mL

7.9239 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

Stock Solution Working Solution

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline

Solubility: ≥ 5 mg/mL (39.62 mM); Clear solution

This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).

Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)

Solubility: ≥ 5 mg/mL (39.62 mM); Clear solution

This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).

Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil

Solubility: ≥ 5 mg/mL (39.62 mM); Clear solution

This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage Dosage
mg/kg
Animal Weight (Per Animal) Animal Weight (Per Animal)
g
Dosing Volume (Per Animal) Dosing Volume (Per Animal)
μL
Number of Animals Number of Animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

%
DMSO +

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
%
+
+
%
Tween-80 + +
%
Saline +

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Working solution concentration: 0.22 mg/mL

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Luo Y, et al. (E)-2-Octenal suppresses the growth of a prochloraz-resistant Penicillium italicum strain and its potential antifungal mechanisms[J]. Postharvest Biology and Technology, 2023, 205: 112515.

[2]. Tan X, et al. (E)-2-Octenal inhibits Neofusicoccum parvum growth by disrupting mitochondrial energy metabolism and is a potential preservative for postharvest mango. Food Res Int. 2025;201:115639. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	7.9239 mL	39.6197 mL	79.2393 mL	198.0983 mL
	5 mM	1.5848 mL	7.9239 mL	15.8479 mL	39.6197 mL
	10 mM	0.7924 mL	3.9620 mL	7.9239 mL	19.8098 mL
	15 mM	0.5283 mL	2.6413 mL	5.2826 mL	13.2066 mL
	20 mM	0.3962 mL	1.9810 mL	3.9620 mL	9.9049 mL
	25 mM	0.3170 mL	1.5848 mL	3.1696 mL	7.9239 mL
	30 mM	0.2641 mL	1.3207 mL	2.6413 mL	6.6033 mL
	40 mM	0.1981 mL	0.9905 mL	1.9810 mL	4.9525 mL
	50 mM	0.1585 mL	0.7924 mL	1.5848 mL	3.9620 mL
	60 mM	0.1321 mL	0.6603 mL	1.3207 mL	3.3016 mL
	80 mM	0.0990 mL	0.4952 mL	0.9905 mL	2.4762 mL
	100 mM	0.0792 mL	0.3962 mL	0.7924 mL	1.9810 mL

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(E)-2-Octenal

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Biological Activity

Chemical Information

Solvent & Solubility

Purity & Documentation

References

Help & FAQs

Complete Stock Solution Preparation Table

(E)-2-Octenal Related Classifications

HY-W134163 Related Classifications