Sptbn2 - spectrin, beta, non-erythrocytic 2 Gene

Also Known as Spnb3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29211

Summary

Predicted to enable actin filament binding activity. Predicted to be a structural constituent of synapse. Involved in cellular response to ethanol and synaptic vesicle exocytosis. Located in several cellular components, including Golgi membrane; cytoplasmic vesicle; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 14 and spinocerebellar ataxia type 5. Orthologous to human SPTBN2 (spectrin beta, non-erythrocytic 2). [provided by Alliance of Genome Resources, Apr 2022]

Sptbn2 Products (1)

mRNA Protein Name
NM_019167.2 NP_062040.2 spectrin beta chain, non-erythrocytic 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
9704016 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to ethanol IEP
IEP: Inferred from expression pattern
12411436 RGD
involved in synaptic vesicle exocytosis IPI
IPI: Inferred from physical interaction
9826670 RGD
Cellular Component GO Annotation Evidence References Source
located in Golgi membrane IDA
IDA: Inferred from direct assay
12411436 RGD
located in endosome IDA
IDA: Inferred from direct assay
12411436 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
12411436 RGD
located in synaptic vesicle IDA
IDA: Inferred from direct assay
9704016 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

spectrin beta chain, non-erythrocytic 2

  • beta SpIII sigma 1

  • beta-III spectrin

  • beta-spectrin 3

  • glutamate transporter EAAT4-associated protein 41

  • spectrin beta chain, brain 2

  • spectrin, non-erythroid beta chain 2

  • spectrin-like protein GTRAP41

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13733 SPTBN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sptbn2 NCBI NCBI:6712