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Cat. No.: HY-147003

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MMV687807

MMV687807 is an anthelmintic agent which has a good activity against Toxoplasma gondii (T. gondii) with an IC₅₀ value of 0.15 μM and a CC₅₀ value of 1.69 μM.

For research use only. We do not sell to patients.

CAS No.: 1417658-11-7
Formula: C₁₅H₈ClF₆NO₂
Molecular Weight:383.67

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (279 KB)

MMV687807 Chemical Structure

CAS No.: 1417658-11-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

MMV687807 is an anthelmintic agent which has a good activity against Toxoplasma gondii (T. gondii) with an IC₅₀ value of 0.15 μM and a CC₅₀ value of 1.69 μM^[1].

IC₅₀ & Target

Toxoplasma

All Parasite Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
Macrophage	IC₅₀	4.9 μM Compound: 30	Cytotoxicity against mouse macrophage cell line J774.1 (ATCC TIB-67) for 3 days by Alamar Blue Cytotoxicity against mouse macrophage cell line J774.1 (ATCC TIB-67) for 3 days by Alamar Blue	[PMID: 23211970]

Chemical Information

CAS No. 1417658-11-7
Molecular Weight 383.67
Formula C₁₅H₈ClF₆NO₂
SMILES

O=C(NC1=CC=C(C(F)(F)F)C(C(F)(F)F)=C1)C2=CC(Cl)=CC=C2O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (279 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Spalenka J, et al. Discovery of New Inhibitors of Toxoplasma gondii via the Pathogen Box. Antimicrob Agents Chemother. 2018;62(2):e01640-17. Published 2018 Jan 25. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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MMV687807

All Parasite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

MMV687807 Related Classifications

HY-147003 Related Classifications