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Cat. No.: HY-12520C

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(S)-SKF 38393

(S)-SKF 38393 is the S-enantiomer of SKF 38393 (HY-12520). (S)-SKF 38393 shows no activity against the D₁ dopamine receptor, with an IC₅₀ of 10700 nM. (S)-SKF 38393 can be used in the research of neurological diseases.

For research use only. We do not sell to patients.

CAS No.: 81702-43-4
Formula: C₁₆H₁₇NO₂
Molecular Weight:255.32

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

(S)-SKF 38393 Chemical Structure

CAS No.: 81702-43-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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- IC₅₀ & Target
- In Vitro
Chemical Information
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Biological Activity

Description

IC₅₀ & Target^[1]

D₁ Receptor

All Dopamine Receptor Isoforms :

In Vitro

(S)-SKF 38393 (Compound 7) shows no activity towards D₁ dopamine receptors in rat brain striatal tissue^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 81702-43-4
Molecular Weight 255.32
Formula C₁₆H₁₇NO₂
SMILES

OC=1C=C2[C@@H](CNCCC2=CC1O)C3=CC=CC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Neumeyer JL, et al. Stereoisomeric probes for the D1 dopamine receptor: synthesis and characterization of R-(+) and S-(-) enantiomers of 3-allyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine and its 6-bromo analogue. J Med Chem. 1992 Apr 17;35(8):1466-71. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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(S)-SKF 38393

All Dopamine Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

(S)-SKF 38393 Related Classifications

HY-12520C Related Classifications