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Cat. No.: HY-124152

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3,4-Dephostatin

(Synonyms: Methyl-3,4-dephostatin)

3,4-Dephostatin (Methyl-3,4-dephostatin) is an inhibitor of protein-tyrosine phosphatase (PTPase). 3,4-Dephostatin accelerates nerve growth factor (NGF)-induced neurite formation in PC12h cells. 3,4-Dephostatin sustains the NGF-induced tyrosine phosphorylation of proteins, most prominently that of mitogen-activated protein (MAP) kinase. 3,4-Dephostatin also prolongs epidermal growth factor (EGF)-induced tyrosine phosphorylation and activation of MAP kinase.

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CAS No.: 173043-84-0
Formule: C₇H₈N₂O₃
Masse moléculaire:168.15

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Data Sheet (266 KB)

3,4-Dephostatin Chemical Structure

CAS No.: 173043-84-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Chemical Information

CAS No. 173043-84-0
Masse moléculaire 168.15
Formule C₇H₈N₂O₃
SMILES

OC1=CC=C(N(C)N=O)C=C1O
Synonyms

Methyl-3,4-dephostatin
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Fujiwara S, et al. Enhancement or induction of neurite formation by a protein tyrosine phosphatase inhibitor, 3,4-dephostatin, in growth factor-treated PC12h cells. Biochem Biophys Res Commun. 1997 Sep 8;238(1):213-7. [Content Brief]

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100 mg

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3,4-Dephostatin

Voir tous les produits spécifiques à Isoform MAP3K

Voir tous les produits spécifiques à Isoform MAP4K

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

3,4-Dephostatin Related Classifications

HY-124152 Related Classifications