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Cat. No.: HY-126108A

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8(S)-HEPE

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Based on 1 Customer Validation

8(S)-HEPE is a monohydroxy fatty acid produced by lipoxygenase oxidation of EPA. It acts to promote hatching of barnacle eggs at 10 nM, although it is not clearly identified as the natural egg hatching factor.

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Pureté: 98.0%
CAS No.: 118492-81-2
Formule: C₂₀H₃₀O₃
Masse moléculaire:318.45

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Solution, -20°C, protect from light, 2 years

8(S)-HEPE Chemical Structure

CAS No.: 118492-81-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- In Vitro
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Activité biologique

Description

Voir tous les produits spécifiques à Isoform Lipoxygenase :

In Vitro

8R-HEPE induces the expression of Abca1 and Abcg1 via activation of liver X receptor, whereas 8S-HEPE elicits no such activity^[2]..

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 118492-81-2
Appearance Liquid
Masse moléculaire 318.45
Formule C₂₀H₃₀O₃
Color Colorless to light yellow
SMILES

CC/C=C\C/C=C\C/C=C\C=C\[C@@H](O)C/C=C\CCCC(O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Solution, -20°C, protect from light, 2 years

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (261 KB)
SDS (393 KB)
- English - EN (393 KB)
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- Norwegian - NO (393 KB)
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- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Hill, et al. Identification and hatching factor activity of monohydroxyeicosapentaenoic acid in homogenates of the barnacle Elminius modestus. Proc. R. Soc. Lond. B Biol. Sci. 234, 455-461 (1988).

[2]. Yamada H, et al. 8(R)-Hydroxyeicosapentaenoic acid (8R-HEPE) induces transcription of cholesterol efflux receptors via activation of liver X receptor in macrophages. Biosci Biotechnol Biochem. 2023 May 19;87(6):584-591. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Activité biologique
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- In Vitro
Chemical Information
Pureté et documentation
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8(S)-HEPE

Voir tous les produits spécifiques à Isoform Lipoxygenase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

8(S)-HEPE Related Classifications

HY-126108A Related Classifications