1. Metabolic Enzyme/Protease
  2. Angiotensin-converting Enzyme (ACE)
  3. (±)8(9)-EpETE

(±)8(9)-EpETE  (Synonyms: (±)8,9-EEQ; (±)8,9-epoxy Eicosatetraenoic acid)

Cat. No.: HY-130309
Handling Instructions Technical Support

Eicosapentaenoic acid (EPA) is converted to epoxyeicosatetraenoic acids (EpETEs) by several cytochrome P450 isoforms. The major product of this epoxygenase pathway, (±)17(18)-EpETE, relaxes vascular and airway smooth muscle by activating large conductance Ca2+-activated K+ (BKCa) channels by directly interacting with BKα channel subunits. (±)8(9)-EpETE is an epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo.

For research use only. We do not sell to patients.

(±)8(9)-EpETE

(±)8(9)-EpETE Chemical Structure

CAS No. : 851378-93-3

Size Price Stock
Solvent
25 μg (314.02 μM * 250 μL in Ethanol) Ask For Quote & Lead Time
Solvent
50 μg (314.02 μM * 500 μL in Ethanol) Ask For Quote & Lead Time
Solvent
100 μg (314.02 μM * 1 mL in Ethanol) Ask For Quote & Lead Time

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Description

Eicosapentaenoic acid (EPA) is converted to epoxyeicosatetraenoic acids (EpETEs) by several cytochrome P450 isoforms. The major product of this epoxygenase pathway, (±)17(18)-EpETE, relaxes vascular and airway smooth muscle by activating large conductance Ca2+-activated K+ (BKCa) channels by directly interacting with BKα channel subunits. (±)8(9)-EpETE is an epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo.

Molecular Weight

318.45

Formula

C20H30O3

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

CC/C=C\C/C=C\C/C=C\CC1C(C/C=C\CCCC(O)=O)O1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Solution, -20°C, 2 years

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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(±)8(9)-EpETE
Cat. No.:
HY-130309
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