(±)8(9)-EpETE

(Synonyms: (±)8,9-EEQ; (±)8,9-epoxy Eicosatetraenoic acid)
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Eicosapentaenoic acid (EPA) is converted to epoxyeicosatetraenoic acids (EpETEs) by several cytochrome P450 isoforms. The major product of this epoxygenase pathway, (±)17(18)-EpETE, relaxes vascular and airway smooth muscle by activating large conductance Ca2+-activated K+ (BKCa) channels by directly interacting with BKα channel subunits. (±)8(9)-EpETE is an epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo.

For research use only. We do not sell to patients.

  • Purity: 99.9%
  • CAS No.: 851378-93-3
  • Formula: C20H30O3
  • Molecular Weight:318.45
  • Storage:

    Solution, -20°C, 2 years

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