118492-81-2
Chemical Structure
8(S)-HEPE
- CAS No.: 118492-81-2
- Formula:C20H30O3
- Molecular Weight:318.45
IUPAC Name: (S,5Z,9E,11Z,14Z,17Z)-8-hydroxyicosa-5,9,11,14,17-pentaenoic acid
InChIKey: WLOUCHKFBGGNEB-CHGUASJCSA-N
SMILES: CC/C=C\C/C=C\C/C=C\C=C\[C@@H](O)C/C=C\CCCC(O)=O
Biological Activity: 8(S)-HEPE is a monohydroxy fatty acid produced by lipoxygenase oxidation of EPA. It acts to promote hatching of barnacle eggs at 10 nM, although it is not clearly identified as the natural egg hatching factor[1][2].
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8(S)-HEPE | 98.0% | 8(S)-HEPE is a monohydroxy fatty acid produced by lipoxygenase oxidation of EPA. It acts to promote hatching of barnacle eggs at 10 nM, although it is not clearly identified as the natural egg hatching factor. | ||||||||||||||||||||
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- [1]. Hill, et al. Identification and hatching factor activity of monohydroxyeicosapentaenoic acid in homogenates of the barnacle Elminius modestus. Proc. R. Soc. Lond. B Biol. Sci. 234, 455-461 (1988).
- [2]. Yamada H, et al. 8(R)-Hydroxyeicosapentaenoic acid (8R-HEPE) induces transcription of cholesterol efflux receptors via activation of liver X receptor in macrophages. Biosci Biotechnol Biochem. 2023 May 19;87(6):584-591. [Content Brief]
Keywords