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Cat. No.: HY-126108A

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8(S)-HEPE

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Based on 1 Customer Validation

8(S)-HEPE is a monohydroxy fatty acid produced by lipoxygenase oxidation of EPA. It acts to promote hatching of barnacle eggs at 10 nM, although it is not clearly identified as the natural egg hatching factor.

For research use only. We do not sell to patients.

Purity: 98.0%
CAS No.: 118492-81-2
Formula: C₂₀H₃₀O₃
Molecular Weight:318.45

Storage:

Solution, -20°C, protect from light, 2 years

8(S)-HEPE Chemical Structure

CAS No.: 118492-81-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
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Classifications
Bioz

Biological Activity

Description

All Lipoxygenase Isoforms :

In Vitro

8R-HEPE induces the expression of Abca1 and Abcg1 via activation of liver X receptor, whereas 8S-HEPE elicits no such activity^[2]..

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 118492-81-2
Appearance Liquid
Molecular Weight 318.45
Formula C₂₀H₃₀O₃
Color Colorless to light yellow
SMILES

CC/C=C\C/C=C\C/C=C\C=C\[C@@H](O)C/C=C\CCCC(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Solution, -20°C, protect from light, 2 years

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (261 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hill, et al. Identification and hatching factor activity of monohydroxyeicosapentaenoic acid in homogenates of the barnacle Elminius modestus. Proc. R. Soc. Lond. B Biol. Sci. 234, 455-461 (1988).

[2]. Yamada H, et al. 8(R)-Hydroxyeicosapentaenoic acid (8R-HEPE) induces transcription of cholesterol efflux receptors via activation of liver X receptor in macrophages. Biosci Biotechnol Biochem. 2023 May 19;87(6):584-591. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References

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8(S)-HEPE

All Lipoxygenase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

8(S)-HEPE Related Classifications

HY-126108A Related Classifications