5(S)-HETE
Based on 1 publication(s) in Google Scholar
5(S)-HETE is an endogenous metabolite present in Blood that can be used for the research of Rheumatoid Arthritis, Rhinitis and Asthma.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 98.9%
- CAS. Nr.: 70608-72-9
- Formel: C20H32O3
- Molecular Weight:320.47
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Speicherung:
Solution, -20°C, 2 years
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HY-107608
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15-KETE -
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15(S)-HEPEAsthma Marker -
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(±)8(9)-EpETEEpoxide -
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12(S)-HETEP38 MAPK/ERK Activator -
HY-120954
14,15-EE-5(Z)-E14,15-EET structural analogue -
HY-130140
8,9-DiHETEEster Product -
HY-130060
12(S)-HETrEPlatelet Aggregation Inhibitor -
HY-118332
19(R)-HETEVasodilator -
HY-130138C
5,6-DiHETEAnti-inflammatory Lipid Mediators -
HY-113711
15-OxoEDEEster Product
Publications Citing Use of MedChemExpress (MCE) 5(S)-HETE
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Biologische Aktivität
Beschreibung
IC50 & Target
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Human Endogenous Metabolite |
In Vitro
Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS. Nr. 70608-72-9
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Appearance Liquid
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Molecular Weight 320.47
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Formel C20H32O3
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Color Colorless to light yellow
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SMILES
CCCCC/C=C\C/C=C\C/C=C\C=C\[C@@H](O)CCCC(O)=O
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Solution, -20°C, 2 years
Publications (1)
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Journal Impact Factor
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Most Recent
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Cell Metab
2026 Jan 9:S1550-4131(25)00546-7. PMID: 41519131
Protokoll
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Collagen-Induced Arthritis
Collagen-induced arthritis (CIA) is an autoimmune murine model of rheumatoid arthritis in which immunization with type II collagen (CII) emulsified in an adjuvant induces a T cell- and autoantibody-driven inflammatory arthritis characterized by synovial hyperplasia, immune cell infiltration, and joint destruction. The model typically relies on genetically susceptible mouse strains (e. g. , DBA/1) and reproduces key features of human rheumatoid arthritis, including anti-collagen immune responses and progressive joint inflammation. Disease onset generally occurs within ~3-4 weeks after immunization, depending on antigen/adjuvant combinations and protocol variation. The immunopathology is driven by adaptive immune activation against CII, leading to systemic and local joint inflammation mediated by pro-inflammatory cytokines and effector immune cells, making CIA a standard preclinical platform for evaluating immunomodulatory and anti-arthritic interventions.
Reinheit & Dokumentation
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Data Sheet (265 KB)
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SDS (393 KB)
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- Français - FR (393 KB)
- Deutsch - DE (393 KB)
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- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
5(S)-HETE Related Classifications
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