5-HETE
Based on 1 Customer Validation
5-HETE ((±)-5-HETE), a fatty acid, is a oxidative derivative of Arachidonic acid. 5-HETE is a mixture of 5(S)-HETE and 5(R)-HETE. 5-HETE is a potent aggregating agent that induces the aggregation of neutrophils with an IC50 value of 200 nM.
For research use only. We do not sell to patients.
- Purity : 96.76%
- CAS No.: 71030-39-2
- Formula: C20H32O3
- Molecular Weight:320.47
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Storage:
Solution, -20°C, 2 years
All Endogenous Metabolite Isoforms
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Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| RBL-1 | IC50 |
77 μM
Compound: 56
|
Inhibition of rat basophilic leukemia-1 (RBL-1) 5-lipoxygenase
Inhibition of rat basophilic leukemia-1 (RBL-1) 5-lipoxygenase
|
[PMID: 3806609] |
Chemical Information
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CAS No. 71030-39-2
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Appearance Liquid
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Molecular Weight 320.47
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Formula C20H32O3
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Color Colorless to light yellow
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SMILES
CCCCC/C=C\C/C=C\C/C=C\C=C\C(O)CCCC(O)=O
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Synonyms
(±)-5-HETE
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, 2 years
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
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Data Sheet (263 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)