71030-39-2
71030-39-2
Chemical Structure
5-HETE
Synonym(s): (±)-5-HETE
- CAS No.: 71030-39-2
- Formula:C20H32O3
- Molecular Weight:320.47
IUPAC Name: (6E,8Z,11Z,14Z)-5-hydroxyicosa-6,8,11,14-tetraenoic acid
InChIKey: KGIJOOYOSFUGPC-XTDASVJISA-N
SMILES: CCCCC/C=C\C/C=C\C/C=C\C=C\C(O)CCCC(O)=O
Biological Activity: 5-HETE ((±)-5-HETE), a fatty acid, is a oxidative derivative of Arachidonic acid. 5-HETE is a mixture of 5(S)-HETE and 5(R)-HETE. 5-HETE is a potent aggregating agent that induces the aggregation of neutrophils with an IC50 value of 200 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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5-HETE | 96.76% | 5-HETE ((±)-5-HETE), a fatty acid, is a oxidative derivative of Arachidonic acid. 5-HETE is a mixture of 5(S)-HETE and 5(R)-HETE. 5-HETE is a potent aggregating agent that induces the aggregation of neutrophils with an IC50 value of 200 nM. | ||||||||||||||||||||
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12S-HHT | 98.45% | 12S-HHT (12(S)-HHTrE) is an enzymatic product of prostaglandin H2 (PGH2) derived from cyclooxygenase (COX)-mediated arachidonic acid metabolism. 12S-HHT is an endogenous ligand for BLT2 that fully activates BLT2 in vivo. 12S-HHT suppresses UV-induced IL-6 synthesis in keratinocytes, exerting an anti-inflammatory activity. | ||||||||||||||||||||
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15(S)-HETE | 98.0% | 15(S)-HETE is an endogenous metabolite present in Urine that can be used for the research of Zellweger Syndrome. | ||||||||||||||||||||
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15(R)-HETE | 99.0% | 15(R)-HETE is an isomer of 15-HETE. 15-HETE is a lipid mediator derived from arachidonic acid and can be used for the study of asthma. | ||||||||||||||||||||
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(±)15-HETE | (±)15-HETE is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. | |||||||||||||||||||||
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5(S)-HETE | 98.9% | 5(S)-HETE is an endogenous metabolite present in Blood that can be used for the research of Rheumatoid Arthritis, Rhinitis and Asthma. | ||||||||||||||||||||
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5(R)-HETE | 5(R)-HETE is a lipoxygenase product of arachidonic acid. 5(R)-HETE is an inducer of neutrophil migration through endothelial and epithelial barriers. 5(R)-HETE is important in mediating lung inflammatory processes. | |||||||||||||||||||||
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5(S)-HPETE | 98.0% | 5(S)-HPETE is a 5-lipoxygenase substrate and Arachidonic acid (HY-109590) metabolite. 5(S)-HPETE forms via 5-LOX-catalyzed hydroperoxidation of arachidonic acid. 5(S)-HPETE undergoes 5-LOX-catalyzed epoxidation (dehydration) to form leukotriene A4. 5(S)-HPETE can be used for the research of asthma, rheumatoid arthritis. | ||||||||||||||||||||
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13(S)-Hydroxy-6(Z),9(Z),11(E)-octadecatrienoic acid | 13(S)-Hydroxy-6(Z),9(Z),11(E)-octadecatrienoic acid is an ester product. | |||||||||||||||||||||
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5-Hydroxy-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic acid,methyl ester | 5-Hydroxy-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic acid,methyl ester is an ester product. | |||||||||||||||||||||
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17(S)-HDoTE | 17(S)-HDoTE is a metabolite of Adrenic acid (HY-W013215). 17(S)-HDoTE is formed by the catalysis of Adrenic acid through 15-lipoxygenase (15-LO). | |||||||||||||||||||||
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