Azo-PROTAC-4C-trans
Azo-PROTAC-4C-trans is a BCR-ABL PROTAC degrader that can efficiently degrade the BCR-ABL fusion protein and ABL protein. Azo-PROTAC-4C-trans exhibits potent selective anti-proliferative activity against K562 cells. Azo-PROTAC-4C-trans allows real-time, reversible regulation of its activity via UV (to inactivate it) /visible light (to activate it) irradiation. Azo-PROTAC-4C-trans can be used for the study of myeloid leukemia.
(Pink: Bcr-Abl ligand (HY-107447); Blue: Cereblon ligand (HY-14658); Black: linker).
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Formule: C50H47ClN12O7S
- Masse moléculaire:995.50
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
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Bcr-Abl |
Abl |
Cereblon |
Chemical Information
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Masse moléculaire 995.50
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Formule C50H47ClN12O7S
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SMILES
O=C(C1=C2C=CC=C1NC(C3=CC=C(/N=N/C4=CC=C(OCCCCN5CCN(C6=CC(NC7=NC=C(C(NC8=C(C)C=CC=C8Cl)=O)S7)=NC(C)=N6)CC5)C=C4)C=C3)=O)N(C(CC9)C(NC9=O)=O)C2=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Azo-PROTAC-4C-trans Related Classifications
HY-180983 Related Classifications
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