CRBN ligand-47
Based on 1 Customer Validation
CRBN ligand-47 is a CRBN-type E3 ubiquitin ligase ligand that can be used to prepare PROTAC.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 99.90%
- CAS No.: 3059455-81-8
- Formule: C11H9BrFNO2
- Masse moléculaire:286.10
-
Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
-
Solvant et solubilité
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
|
Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 3059455-81-8
-
Appearance Solid
-
Masse moléculaire 286.10
-
Formule C11H9BrFNO2
-
Color White to off-white
-
SMILES
BrC(C=CC(C1C(NC(CC1)=O)=O)=C2)=C2F
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : 100 mg/mL (349.53 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
-
Fiche technique (272 KB)
-
SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
-
Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4953 mL | 17.4764 mL | 34.9528 mL | 87.3820 mL |
| 5 mM | 0.6991 mL | 3.4953 mL | 6.9906 mL | 17.4764 mL | |
| 10 mM | 0.3495 mL | 1.7476 mL | 3.4953 mL | 8.7382 mL | |
| 15 mM | 0.2330 mL | 1.1651 mL | 2.3302 mL | 5.8255 mL | |
| 20 mM | 0.1748 mL | 0.8738 mL | 1.7476 mL | 4.3691 mL | |
| 25 mM | 0.1398 mL | 0.6991 mL | 1.3981 mL | 3.4953 mL | |
| 30 mM | 0.1165 mL | 0.5825 mL | 1.1651 mL | 2.9127 mL | |
| 40 mM | 0.0874 mL | 0.4369 mL | 0.8738 mL | 2.1846 mL | |
| 50 mM | 0.0699 mL | 0.3495 mL | 0.6991 mL | 1.7476 mL | |
| 60 mM | 0.0583 mL | 0.2913 mL | 0.5825 mL | 1.4564 mL | |
| 80 mM | 0.0437 mL | 0.2185 mL | 0.4369 mL | 1.0923 mL | |
| 100 mM | 0.0350 mL | 0.1748 mL | 0.3495 mL | 0.8738 mL |
CRBN ligand-47 Related Classifications
HY-170108 Related Classifications
Powered by Bioz