PfSUB1-IN-1
PfSUB1-IN-1 (compound 4c) is a plasmodium falciparum subtilisin-like serine protease 1 (PfSUB1) Inhibitor (IC50: 15 nM). PfSUB1 is an antimalarial target. PfSUB1-IN-1 inhibits the growth of a genetically modified P. falciparum line expressing reduced levels of PfSUB1 13-fold more efficiently compared to a wild-type parasite line.
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- Formule: C28H41BN4O7
- Masse moléculaire:556.46
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | CC50 |
296 μM
Compound: 4c
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Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 48 hrs by resazurin dye based spectraMax M5 microplate reader analysis
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 48 hrs by resazurin dye based spectraMax M5 microplate reader analysis
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[PMID: 39051854] |
Chemical Information
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Masse moléculaire 556.46
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Formule C28H41BN4O7
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SMILES
O=C(N[C@@H](C1CCCC1)C(N[C@@H]([C@@H](C)CC)C(NCC(N[C@@H](CC2)B(O)OC2=O)=O)=O)=O)C3=CC(C)=CC(C)=C3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PfSUB1-IN-1 Related Classifications
HY-159479 Related Classifications
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